Interaction of Age and Mechanical Stability on Bone Defect Healing: An Early Transcriptional Analysis of Fracture Hematoma in Rat

Andrea Ode; Georg N. Duda; Sven Geissler; Stephan Pauly; Jan-Erik Ode; Carsten Perka; Patrick Strube

doi:10.1371/journal.pone.0106462

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Peer-reviewed

Research Article

Interaction of Age and Mechanical Stability on Bone Defect Healing: An Early Transcriptional Analysis of Fracture Hematoma in Rat

Andrea Ode,

Affiliations Julius Wolff Institute, Charité - Universitätsmedizin, Berlin, Germany, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany
⨯
Georg N. Duda ,

* E-mail: Georg.Duda@charite.de

Affiliations Julius Wolff Institute, Charité - Universitätsmedizin, Berlin, Germany, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany, Klinik für Orthopädie, Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin, Berlin, Germany
⨯
Sven Geissler,

Affiliations Julius Wolff Institute, Charité - Universitätsmedizin, Berlin, Germany, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany
⨯
Stephan Pauly,

Affiliations Julius Wolff Institute, Charité - Universitätsmedizin, Berlin, Germany, Klinik für Orthopädie, Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin, Berlin, Germany
⨯
Jan-Erik Ode,

Affiliation Julius Wolff Institute, Charité - Universitätsmedizin, Berlin, Germany
⨯
Carsten Perka,

Affiliations Julius Wolff Institute, Charité - Universitätsmedizin, Berlin, Germany, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany, Klinik für Orthopädie, Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin, Berlin, Germany
⨯
Patrick Strube

Affiliations Julius Wolff Institute, Charité - Universitätsmedizin, Berlin, Germany, Klinik für Orthopädie, Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin, Berlin, Germany
⨯

Interaction of Age and Mechanical Stability on Bone Defect Healing: An Early Transcriptional Analysis of Fracture Hematoma in Rat

Andrea Ode,
Georg N. Duda,
Sven Geissler,
Stephan Pauly,
Jan-Erik Ode,
Carsten Perka,
Patrick Strube

Published: September 4, 2014
https://doi.org/10.1371/journal.pone.0106462

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Bone fracture
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Gene expression
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Cell migration
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Bone and joint mechanics
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Regeneration
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Stiffness
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