Monte-Carlo Modeling of the Central Carbon Metabolism of Lactococcus lactis: Insights into Metabolic Regulation

Ettore Murabito; Malkhey Verma; Martijn Bekker; Domenico Bellomo; Hans V. Westerhoff; Bas Teusink; Ralf Steuer

doi:10.1371/journal.pone.0106453

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Open Access

Peer-reviewed

Research Article

Monte-Carlo Modeling of the Central Carbon Metabolism of Lactococcus lactis: Insights into Metabolic Regulation

Ettore Murabito ,

* E-mail: ettore.murabito@manchester.ac.uk (EM); ralf.steuer@hu-berlin.de (RS)

Affiliation Manchester Institute of Biotechnology, School of Chemical Engineering and Analytical Sciences (CEAS), Manchester Centre for Integrative Systems Biology (MCISB), The University of Manchester, Manchester, United Kingdom
⨯
Malkhey Verma,

Affiliation Manchester Institute of Biotechnology, School of Chemical Engineering and Analytical Sciences (CEAS), Manchester Centre for Integrative Systems Biology (MCISB), The University of Manchester, Manchester, United Kingdom
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Martijn Bekker,

Affiliation Molecular Microbial Physiology, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands
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Domenico Bellomo,

Affiliation Systems Bioinformatics IBIVU and Netherlands Institute for Systems Biology (NISB), VU University Amsterdam, Amsterdam, The Netherlands
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Hans V. Westerhoff,

Affiliations Manchester Institute of Biotechnology, School of Chemical Engineering and Analytical Sciences (CEAS), Manchester Centre for Integrative Systems Biology (MCISB), The University of Manchester, Manchester, United Kingdom, Synthetic Systems Biology, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands, Molecular Cell Physiology, FALW, VU University Amsterdam, Amsterdam, The Netherlands
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Bas Teusink,

Affiliation Systems Bioinformatics IBIVU and Netherlands Institute for Systems Biology (NISB), VU University Amsterdam, Amsterdam, The Netherlands
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Ralf Steuer

* E-mail: ettore.murabito@manchester.ac.uk (EM); ralf.steuer@hu-berlin.de (RS)

Affiliations CzechGlobe - Global Change Research Center, Academy of Sciences of the Czech Republic, Brno, Czech Republic, Humboldt-University Berlin, Institute for Theoretical Biology, Berlin, Germany
⨯

Monte-Carlo Modeling of the Central Carbon Metabolism of Lactococcus lactis: Insights into Metabolic Regulation

Ettore Murabito,
Malkhey Verma,
Martijn Bekker,
Domenico Bellomo,
Hans V. Westerhoff,
Bas Teusink,
Ralf Steuer

Published: September 30, 2014
https://doi.org/10.1371/journal.pone.0106453

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06 Oct 2014
20:13 GMT
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Figure 3 is not reproduced correctly Posted by steuer on 06 Oct 2014 at 20:13 GMT

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Glucose metabolism
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Glucose
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Lactococcus lactis
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