Immunohistochemical Analysis of the Mechanistic Target of Rapamycin and Hypoxia Signalling Pathways in Basal Cell Carcinoma and Trichoepithelioma

Tjinta Brinkhuizen; Chantal A. H. Weijzen; Jonathan Eben; Monique R. Thissen; Ariënne M. van Marion; Björn G. Lohman; Véronique J. L. Winnepenninckx; Patty J. Nelemans; Maurice A. M. van Steensel

doi:10.1371/journal.pone.0106427

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Open Access

Peer-reviewed

Research Article

Immunohistochemical Analysis of the Mechanistic Target of Rapamycin and Hypoxia Signalling Pathways in Basal Cell Carcinoma and Trichoepithelioma

Tjinta Brinkhuizen ,

* E-mail: t.brinkhuizen@mumc.nl

Affiliations Department of Dermatology, Maastricht University Medical Centre, Maastricht, the Netherlands, GROW, School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
⨯
Chantal A. H. Weijzen,

Affiliations Department of Dermatology, Maastricht University Medical Centre, Maastricht, the Netherlands, GROW, School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
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Jonathan Eben,

Affiliations Department of Pathology, Maastricht University Medical Centre, Maastricht, the Netherlands, GROW, School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
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Monique R. Thissen,

Affiliations Department of Dermatology, Maastricht University Medical Centre, Maastricht, the Netherlands, GROW, School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
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Ariënne M. van Marion,

Affiliation Department of Pathology, VieCuri medical Centre, Venlo, the Netherlands
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Björn G. Lohman,

Affiliation Department of Pathology, Laurentius Hospital, Roermond, the Netherlands
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Véronique J. L. Winnepenninckx,

Affiliations Department of Pathology, Maastricht University Medical Centre, Maastricht, the Netherlands, GROW, School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
⨯
Patty J. Nelemans,

Affiliations Department of Epidemiology, Maastricht University Medical Centre, Maastricht, the Netherlands, GROW, School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
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Maurice A. M. van Steensel

Affiliations Department of Dermatology, Maastricht University Medical Centre, Maastricht, the Netherlands, Department of Clinical Genetics, Maastricht University Medical Centre, Maastricht, the Netherlands, GROW, School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands, Institute of Medical Biology, Immunos, Singapore, Singapore
⨯

Immunohistochemical Analysis of the Mechanistic Target of Rapamycin and Hypoxia Signalling Pathways in Basal Cell Carcinoma and Trichoepithelioma

Tjinta Brinkhuizen,
Chantal A. H. Weijzen,
Jonathan Eben,
Monique R. Thissen,
Ariënne M. van Marion,
Björn G. Lohman,
Véronique J. L. Winnepenninckx,
Patty J. Nelemans,
Maurice A. M. van Steensel

Published: September 2, 2014
https://doi.org/10.1371/journal.pone.0106427

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Basal cell carcinomas
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Malignant tumors
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Hypoxia
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Cell staining
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Membrane proteins
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Cancers and neoplasms
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Immunohistochemical analysis
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