Major Molecular Response Achievement in CML Patients Can Be Predicted by BCR-ABL1/ABL1 or BCR-ABL1/GUS Ratio at an Earlier Time Point of Follow-Up than Currently Recommended

Sarah Huet; Pascale Cony-Makhoul; Maël Heiblig; Isabelle Tigaud; Sophie Gazzo; Amine Belhabri; Denis Souche; Mauricette Michallet; Jean-Pierre Magaud; Sandrine Hayette; Franck Nicolini

doi:10.1371/journal.pone.0106250

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Open Access

Peer-reviewed

Research Article

Major Molecular Response Achievement in CML Patients Can Be Predicted by BCR-ABL1/ABL1 or BCR-ABL1/GUS Ratio at an Earlier Time Point of Follow-Up than Currently Recommended

Sarah Huet ,

* E-mail: sarah.huet@chu-lyon.fr

Affiliations Laboratoire d'hématologie, Centre de Biologie Sud, Centre Hospitalier Lyon Sud, Pierre-Benite, France, Unité Mixte de Recherche 5239 Centre National de la Recherche Scientifique, Faculté de médecine Lyon Sud, Oullins, France
⨯
Pascale Cony-Makhoul,

Affiliation Service clinique d'hématologie, Centre Hospitalier d'Annecy, Pringy, France
⨯
Maël Heiblig,

Affiliation Service clinique d'hématologie 1G, Centre Hospitalier Lyon Sud, Pierre-Benite, France
⨯
Isabelle Tigaud,

Affiliation Laboratoire d'hématologie, Centre de Biologie Sud, Centre Hospitalier Lyon Sud, Pierre-Benite, France
⨯
Sophie Gazzo,

Affiliation Laboratoire d'hématologie, Centre de Biologie Sud, Centre Hospitalier Lyon Sud, Pierre-Benite, France
⨯
Amine Belhabri,

Affiliation Service clinique d'hématologie, Centre Régional de Lutte Contre le Cancer Léon Bérard, Lyon, France
⨯
Denis Souche,

Affiliation Laboratoire d'hématologie, Centre de Biologie Sud, Centre Hospitalier Lyon Sud, Pierre-Benite, France
⨯
Mauricette Michallet,

Affiliation Service clinique d'hématologie 1G, Centre Hospitalier Lyon Sud, Pierre-Benite, France
⨯
Jean-Pierre Magaud,

Affiliations Laboratoire d'hématologie, Centre de Biologie Sud, Centre Hospitalier Lyon Sud, Pierre-Benite, France, Unité Mixte de Recherche 5239 Centre National de la Recherche Scientifique, Faculté de médecine Lyon Sud, Oullins, France
⨯
Sandrine Hayette,

Affiliations Laboratoire d'hématologie, Centre de Biologie Sud, Centre Hospitalier Lyon Sud, Pierre-Benite, France, Unité Mixte de Recherche 5239 Centre National de la Recherche Scientifique, Faculté de médecine Lyon Sud, Oullins, France
⨯
Franck Nicolini

Affiliation Service clinique d'hématologie 1G, Centre Hospitalier Lyon Sud, Pierre-Benite, France
⨯

Major Molecular Response Achievement in CML Patients Can Be Predicted by BCR-ABL1/ABL1 or BCR-ABL1/GUS Ratio at an Earlier Time Point of Follow-Up than Currently Recommended

Sarah Huet,
Pascale Cony-Makhoul,
Maël Heiblig,
Isabelle Tigaud,
Sophie Gazzo,
Amine Belhabri,
Denis Souche,
Mauricette Michallet,
Jean-Pierre Magaud,
Sandrine Hayette

Published: September 9, 2014
https://doi.org/10.1371/journal.pone.0106250

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