Oxymatrine Improves Intestinal Epithelial Barrier Function Involving NF-κB-Mediated Signaling Pathway in CCl4-Induced Cirrhotic Rats

Jian-Bo Wen; Fang-Qing Zhu; Wei-Guo Chen; Li-Ping Jiang; Jie Chen; Zhao-Peng Hu; Yong-Jian Huang; Zhi-Wei Zhou; Gui-Liang Wang; Hao Lin; Shu-Feng Zhou

doi:10.1371/journal.pone.0106082

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Open Access

Peer-reviewed

Research Article

Oxymatrine Improves Intestinal Epithelial Barrier Function Involving NF-κB-Mediated Signaling Pathway in CCl₄-Induced Cirrhotic Rats

Jian-Bo Wen ,

* E-mail: wenjbpx@126.com (JBW); szhou@health.usf.edu (SFZ)

Affiliation Department of Gastroenterology, the Affiliated Pingxiang Hospital of Southern Medical University, Pingxiang, Jiangxi, China
⨯
Fang-Qing Zhu,

Affiliation Department of Gastroenterology, the Affiliated Pingxiang Hospital of Southern Medical University, Pingxiang, Jiangxi, China
⨯
Wei-Guo Chen,

Affiliation Department of Gastroenterology, the Affiliated Pingxiang Hospital of Southern Medical University, Pingxiang, Jiangxi, China
⨯
Li-Ping Jiang,

Affiliation Animal Laboratory, the Affiliated Pingxiang Hospital of Southern Medical University, Pingxiang, Jiangxi, China
⨯
Jie Chen,

Affiliation Department of Pharmacology, the Affiliated Pingxiang Hospital of Southern Medical University, Pingxiang, Jiangxi, China
⨯
Zhao-Peng Hu,

Affiliation Department of Pathology, the Affiliated Pingxiang Hospital of Southern Medical University, Pingxiang, Jiangxi, China
⨯
Yong-Jian Huang,

Affiliation Department of Clinical Laboratory, the Affiliated Pingxiang Hospital of Southern Medical University, Pingxiang, Jiangxi, China
⨯
Zhi-Wei Zhou,

Affiliation Department of Pharmaceutical Science, College of Pharmacy, University of South Florida, Tampa, Florida, United States of America
⨯
Gui-Liang Wang,

Affiliation Department of Gastroenterology, the Affiliated Pingxiang Hospital of Southern Medical University, Pingxiang, Jiangxi, China
⨯
Hao Lin,

Affiliation Department of Gastroenterology, the Affiliated Pingxiang Hospital of Southern Medical University, Pingxiang, Jiangxi, China
⨯
Shu-Feng Zhou

* E-mail: wenjbpx@126.com (JBW); szhou@health.usf.edu (SFZ)

Affiliation Department of Pharmaceutical Science, College of Pharmacy, University of South Florida, Tampa, Florida, United States of America
⨯

Oxymatrine Improves Intestinal Epithelial Barrier Function Involving NF-κB-Mediated Signaling Pathway in CCl₄-Induced Cirrhotic Rats

Jian-Bo Wen,
Fang-Qing Zhu,
Wei-Guo Chen,
Li-Ping Jiang,
Jie Chen,
Zhao-Peng Hu,
Yong-Jian Huang,
Zhi-Wei Zhou,
Gui-Liang Wang,
Hao Lin

Published: August 29, 2014
https://doi.org/10.1371/journal.pone.0106082

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