Heat-Stable Molecule Derived from Streptococcus cristatus Induces APOBEC3 Expression and Inhibits HIV-1 Replication

Ziqing Wang; Yi Luo; Qiujia Shao; Ballington L. Kinlock; Chenliang Wang; James E. K. Hildreth; Hua Xie; Bindong Liu

doi:10.1371/journal.pone.0106078

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Peer-reviewed

Research Article

Heat-Stable Molecule Derived from Streptococcus cristatus Induces APOBEC3 Expression and Inhibits HIV-1 Replication

Ziqing Wang ,

Contributed equally to this work with: Ziqing Wang, Yi Luo

Current address: Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas United States of America

Affiliation Center for AIDS Health Disparities Research, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Yi Luo ,

Contributed equally to this work with: Ziqing Wang, Yi Luo

Affiliation Center for AIDS Health Disparities Research, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Qiujia Shao,

Affiliation Center for AIDS Health Disparities Research, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Ballington L. Kinlock,

Affiliation Center for AIDS Health Disparities Research, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Chenliang Wang,

Affiliations Center for AIDS Health Disparities Research, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America, Institute of Gastroenterology and Institute of Human Virology, Sun Yat-sen University, Guangzhou, Guangdong, Peoples of Republic of China
⨯
James E. K. Hildreth,

Current address: College of Biological Sciences, University of California Davis, Davis, California, United States of America

Affiliation Center for AIDS Health Disparities Research, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Hua Xie ,

* E-mail: bliu@mmc.edu (BL); hxie@mmc.edu (HX)

Affiliation Department of Oral Biology and Research, School of Dentistry, Meharry Medical College, Nashville, Tennessee, United States of America
⨯
Bindong Liu

* E-mail: bliu@mmc.edu (BL); hxie@mmc.edu (HX)

Affiliation Center for AIDS Health Disparities Research, School of Medicine, Meharry Medical College, Nashville, Tennessee, United States of America
⨯

Heat-Stable Molecule Derived from Streptococcus cristatus Induces APOBEC3 Expression and Inhibits HIV-1 Replication

Ziqing Wang,
Yi Luo,
Qiujia Shao,
Ballington L. Kinlock,
Chenliang Wang,
James E. K. Hildreth,
Hua Xie,
Bindong Liu

Published: August 28, 2014
https://doi.org/10.1371/journal.pone.0106078

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