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Open Access
Peer-reviewed
Research Article
Extracellular Matrix Defects in Aneurysmal Fibulin-4 Mice Predispose to Lung Emphysema
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Natasja W. M. Ramnath,
Affiliations Department of Genetics, Cancer Genomics Centre, Erasmus MC, Rotterdam, The Netherlands, Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands
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Koen M. van de Luijtgaarden,
Affiliation Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands
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Ingrid van der Pluijm,
Affiliations Department of Genetics, Cancer Genomics Centre, Erasmus MC, Rotterdam, The Netherlands, Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands
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Menno van Nimwegen,
Affiliation Department of Pulmonary Diseases, Erasmus MC, Rotterdam, The Netherlands
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Paula M. van Heijningen,
Affiliation Department of Genetics, Cancer Genomics Centre, Erasmus MC, Rotterdam, The Netherlands
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Sigrid M. A. Swagemakers,
Affiliations Department of Genetics, Cancer Genomics Centre, Erasmus MC, Rotterdam, The Netherlands, Department of Bioinformatics, Erasmus MC, Rotterdam, The Netherlands
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Bibi S. van Thiel,
Affiliations Department of Genetics, Cancer Genomics Centre, Erasmus MC, Rotterdam, The Netherlands, Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands, Department of Pharmacology, Erasmus MC, Rotterdam, The Netherlands
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Ruziedi Y. Ridwan,
Affiliations Department of Genetics, Cancer Genomics Centre, Erasmus MC, Rotterdam, The Netherlands, Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands, Department of Pharmacology, Erasmus MC, Rotterdam, The Netherlands
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Nicole van Vliet,
Affiliation Department of Genetics, Cancer Genomics Centre, Erasmus MC, Rotterdam, The Netherlands
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Marcel Vermeij,
Affiliation Department of Pathology, Erasmus MC, Rotterdam, The Netherlands
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Luuk J. A. C. Hawinkels,
Affiliation Department of Molecular Cell Biology and Centre for Biomedical Genetics, Leiden, The Netherlands
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Anne de Munck,
Affiliation Department of Pediatric Surgery, Erasmus MC, Rotterdam, The Netherlands
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Oleh Dzyubachyk,
Affiliations Department of Medical Informatics and Department of Radiology, Erasmus MC, Rotterdam, The Netherlands, Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands
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Erik Meijering,
Affiliation Department of Medical Informatics and Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
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Peter van der Spek,
Affiliation Department of Bioinformatics, Erasmus MC, Rotterdam, The Netherlands
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Robbert Rottier,
Affiliation Department of Pediatric Surgery, Erasmus MC, Rotterdam, The Netherlands
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Hiromi Yanagisawa,
Affiliation Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
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Rudi W. Hendriks,
Affiliation Department of Pulmonary Diseases, Erasmus MC, Rotterdam, The Netherlands
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Roland Kanaar,
Affiliations Department of Genetics, Cancer Genomics Centre, Erasmus MC, Rotterdam, The Netherlands, Department of Radiation Oncology, Erasmus MC, Rotterdam, The Netherlands
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Ellen V. Rouwet,
Affiliation Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands
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Alex Kleinjan ,
* E-mail: j.essers@erasmusmc.nl (JE); a.kleinjan@erasmusmc.nl (AK)
Affiliation Department of Pulmonary Diseases, Erasmus MC, Rotterdam, The Netherlands
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Jeroen Essers
* E-mail: j.essers@erasmusmc.nl (JE); a.kleinjan@erasmusmc.nl (AK)
Affiliations Department of Genetics, Cancer Genomics Centre, Erasmus MC, Rotterdam, The Netherlands, Department of Radiation Oncology, Erasmus MC, Rotterdam, The Netherlands, Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands
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Extracellular Matrix Defects in Aneurysmal Fibulin-4 Mice Predispose to Lung Emphysema
- Natasja W. M. Ramnath,
- Koen M. van de Luijtgaarden,
- Ingrid van der Pluijm,
- Menno van Nimwegen,
- Paula M. van Heijningen,
- Sigrid M. A. Swagemakers,
- Bibi S. van Thiel,
- Ruziedi Y. Ridwan,
- Nicole van Vliet,
- Marcel Vermeij
- Published: September 25, 2014
- https://doi.org/10.1371/journal.pone.0106054