Epigenetic Switch at Atp2a2 and Myh7 Gene Promoters in Pressure Overload-Induced Heart Failure

Tiziana Angrisano; Gabriele Giacomo Schiattarella; Simona Keller; Gianluigi Pironti; Ermanno Florio; Fabio Magliulo; Roberta Bottino; Raffaela Pero; Francesca Lembo; Enrico Vittorio Avvedimento; Giovanni Esposito; Bruno Trimarco; Lorenzo Chiariotti; Cinzia Perrino

doi:10.1371/journal.pone.0106024

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Open Access

Peer-reviewed

Research Article

Epigenetic Switch at Atp2a2 and Myh7 Gene Promoters in Pressure Overload-Induced Heart Failure

Tiziana Angrisano ,

Contributed equally to this work with: Tiziana Angrisano, Gabriele Giacomo Schiattarella

Affiliations Department of Molecular Medicine and Medical Biotechnology, Federico II University, Naples, Italy, Department of Biology, Federico II University, Naples, Italy
⨯
Gabriele Giacomo Schiattarella ,

Contributed equally to this work with: Tiziana Angrisano, Gabriele Giacomo Schiattarella

Affiliation Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
⨯
Simona Keller,

Affiliation Department of Molecular Medicine and Medical Biotechnology, Federico II University, Naples, Italy
⨯
Gianluigi Pironti,

Affiliations Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Ermanno Florio,

Affiliation Department of Molecular Medicine and Medical Biotechnology, Federico II University, Naples, Italy
⨯
Fabio Magliulo,

Affiliation Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
⨯
Roberta Bottino,

Affiliation Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
⨯
Raffaela Pero,

Affiliation Department of Molecular Medicine and Medical Biotechnology, Federico II University, Naples, Italy
⨯
Francesca Lembo,

Affiliation Department of Molecular Medicine and Medical Biotechnology, Federico II University, Naples, Italy
⨯
Enrico Vittorio Avvedimento,

Affiliation Department of Molecular Medicine and Medical Biotechnology, Federico II University, Naples, Italy
⨯
Giovanni Esposito,

Affiliation Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
⨯
Bruno Trimarco,

Affiliation Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
⨯
Lorenzo Chiariotti ,

* E-mail: chiariot@unina.it (LC); perrino@unina.it (CP)

Affiliation Department of Molecular Medicine and Medical Biotechnology, Federico II University, Naples, Italy
⨯
Cinzia Perrino

* E-mail: chiariot@unina.it (LC); perrino@unina.it (CP)

Affiliation Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
⨯

Epigenetic Switch at Atp2a2 and Myh7 Gene Promoters in Pressure Overload-Induced Heart Failure

Tiziana Angrisano,
Gabriele Giacomo Schiattarella,
Simona Keller,
Gianluigi Pironti,
Ermanno Florio,
Fabio Magliulo,
Roberta Bottino,
Raffaela Pero,
Francesca Lembo,
Enrico Vittorio Avvedimento

Published: September 2, 2014
https://doi.org/10.1371/journal.pone.0106024

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DNA methylation
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Epigenetics
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Heart failure
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Heart
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Gene expression
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