Cleavage Specificity Analysis of Six Type II Transmembrane Serine Proteases (TTSPs) Using PICS with Proteome-Derived Peptide Libraries

Olivier Barré; Antoine Dufour; Ulrich Eckhard; Reinhild Kappelhoff; François Béliveau; Richard Leduc; Christopher M. Overall

doi:10.1371/journal.pone.0105984

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Peer-reviewed

Research Article

Cleavage Specificity Analysis of Six Type II Transmembrane Serine Proteases (TTSPs) Using PICS with Proteome-Derived Peptide Libraries

Olivier Barré ,

Contributed equally to this work with: Olivier Barré, Antoine Dufour, Ulrich Eckhard, Reinhild Kappelhoff

Affiliation Centre for Blood Research, Department of Oral Biological & Medical Sciences, University of British Columbia, Vancouver, BC, Canada
⨯
Antoine Dufour ,

Contributed equally to this work with: Olivier Barré, Antoine Dufour, Ulrich Eckhard, Reinhild Kappelhoff

Affiliation Centre for Blood Research, Department of Oral Biological & Medical Sciences, University of British Columbia, Vancouver, BC, Canada
⨯
Ulrich Eckhard ,

Contributed equally to this work with: Olivier Barré, Antoine Dufour, Ulrich Eckhard, Reinhild Kappelhoff

Affiliation Centre for Blood Research, Department of Oral Biological & Medical Sciences, University of British Columbia, Vancouver, BC, Canada
⨯
Reinhild Kappelhoff ,

Contributed equally to this work with: Olivier Barré, Antoine Dufour, Ulrich Eckhard, Reinhild Kappelhoff

Affiliation Centre for Blood Research, Department of Oral Biological & Medical Sciences, University of British Columbia, Vancouver, BC, Canada
⨯
François Béliveau,

Affiliation Department of Pharmacology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada
⨯
Richard Leduc,

Affiliation Department of Pharmacology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada
⨯
Christopher M. Overall

* E-mail: chris.overall@ubc.ca

Affiliations Centre for Blood Research, Department of Oral Biological & Medical Sciences, University of British Columbia, Vancouver, BC, Canada, Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada
⨯

Cleavage Specificity Analysis of Six Type II Transmembrane Serine Proteases (TTSPs) Using PICS with Proteome-Derived Peptide Libraries

Olivier Barré,
Antoine Dufour,
Ulrich Eckhard,
Reinhild Kappelhoff,
François Béliveau,
Richard Leduc,
Christopher M. Overall

Published: September 11, 2014
https://doi.org/10.1371/journal.pone.0105984

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Proteases
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Peptide libraries
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Lysine
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Serine proteases
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Arginine
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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
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Synthetic peptides
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Proteomic databases
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