Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice

Guillaume P. Dugué; Magor L. Lörincz; Eran Lottem; Enrica Audero; Sara Matias; Patricia A. Correia; Clément Léna; Zachary F. Mainen

doi:10.1371/journal.pone.0105941

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Peer-reviewed

Research Article

Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice

Guillaume P. Dugué ,

* E-mail: gdugue@biologie.ens.fr (GPD); zmainen@neuro.fchampalimaud.org (ZFM)

Affiliations Champalimaud Neuroscience Programme, Champalimaud Center for the Unknown, Lisbon, Portugal, Institut de Biologie de l'Ecole Normale Supérieure, Centre National de la Recherche Scientifique (CNRS) UMR8197, Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Paris, France
⨯
Magor L. Lörincz,

Affiliations Champalimaud Neuroscience Programme, Champalimaud Center for the Unknown, Lisbon, Portugal, MTA-SZTE Research Group for Cortical Microcircuits, Department of Physiology, University of Szeged, Szeged, Hungary
⨯
Eran Lottem,

Affiliation Champalimaud Neuroscience Programme, Champalimaud Center for the Unknown, Lisbon, Portugal
⨯
Enrica Audero,

Affiliation Champalimaud Neuroscience Programme, Champalimaud Center for the Unknown, Lisbon, Portugal
⨯
Sara Matias,

Affiliation Champalimaud Neuroscience Programme, Champalimaud Center for the Unknown, Lisbon, Portugal
⨯
Patricia A. Correia,

Affiliation Champalimaud Neuroscience Programme, Champalimaud Center for the Unknown, Lisbon, Portugal
⨯
Clément Léna ,

Contributed equally to this work with: Clément Léna, Zachary F. Mainen

Affiliation Institut de Biologie de l'Ecole Normale Supérieure, Centre National de la Recherche Scientifique (CNRS) UMR8197, Institut National de la Santé et de la Recherche Médicale (INSERM) U1024, Paris, France
⨯
Zachary F. Mainen

Contributed equally to this work with: Clément Léna, Zachary F. Mainen

* E-mail: gdugue@biologie.ens.fr (GPD); zmainen@neuro.fchampalimaud.org (ZFM)

Affiliation Champalimaud Neuroscience Programme, Champalimaud Center for the Unknown, Lisbon, Portugal
⨯

Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice

Guillaume P. Dugué,
Magor L. Lörincz,
Eran Lottem,
Enrica Audero,
Sara Matias,
Patricia A. Correia,
Clément Léna,
Zachary F. Mainen

Published: August 22, 2014
https://doi.org/10.1371/journal.pone.0105941

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