Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes

Synnøve Magnussen; Elin Hadler-Olsen; Nadezhda Latysheva; Emma Pirila; Sonja E. Steigen; Robert Hanes; Tuula Salo; Jan-Olof Winberg; Lars Uhlin-Hansen; Gunbjørg Svineng

doi:10.1371/journal.pone.0105929

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Peer-reviewed

Research Article

Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes

Synnøve Magnussen ,

* E-mail: synnove.magnussen@uit.no

Affiliation Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway
⨯
Elin Hadler-Olsen,

Affiliation Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway
⨯
Nadezhda Latysheva,

Affiliation Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway
⨯
Emma Pirila,

Affiliation Department of Diagnostics and Oral Medicine, Institute of Dentistry, University of Oulu, and Medical Research Center, Oulu University Hospital, Oulu, Finland
⨯
Sonja E. Steigen,

Affiliations Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway, Diagnostic Clinic - Department of Clinical Pathology, University Hospital of North Norway, Tromsø, Norway
⨯
Robert Hanes,

Affiliation Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway
⨯
Tuula Salo,

Affiliations Department of Diagnostics and Oral Medicine, Institute of Dentistry, University of Oulu, and Medical Research Center, Oulu University Hospital, Oulu, Finland, Institute of Dentistry, University of Helsinki, Helsinki, Finland
⨯
Jan-Olof Winberg,

Affiliation Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway
⨯
Lars Uhlin-Hansen,

Affiliations Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway, Diagnostic Clinic - Department of Clinical Pathology, University Hospital of North Norway, Tromsø, Norway
⨯
Gunbjørg Svineng

Affiliation Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway
⨯

Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes

Synnøve Magnussen,
Elin Hadler-Olsen,
Nadezhda Latysheva,
Emma Pirila,
Sonja E. Steigen,
Robert Hanes,
Tuula Salo,
Jan-Olof Winberg,
Lars Uhlin-Hansen,
Gunbjørg Svineng

Published: August 26, 2014
https://doi.org/10.1371/journal.pone.0105929

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