Spontaneous Genomic Alterations in a Chimeric Model of Colorectal Cancer Enable Metastasis and Guide Effective Combinatorial Therapy

• Yinghui Zhou ,

  Contributed equally to this work with: Yinghui Zhou, William M. Rideout III

  * E-mail: yinghuizhou01@gmail.com

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• William M. Rideout III ,

  Contributed equally to this work with: Yinghui Zhou, William M. Rideout III

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Angela Bressel,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Sireesha Yalavarthi,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Tong Zi,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Darren Potz,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Samuel Farlow,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Joelle Brodeur,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Anthony Monti,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Shailaja Reddipalli,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Qiurong Xiao,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Steve Bottega,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Bin Feng,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• M. Isabel Chiu,

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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• Marcus Bosenberg,

  Affiliation Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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•  [ ... ],
• Joerg Heyer

  Affiliation Department of Research, AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America

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