Antidiabetic Property of Symplocos cochinchinensis Is Mediated by Inhibition of Alpha Glucosidase and Enhanced Insulin Sensitivity

Kalathookunnel Antony Antu; Mariam Philip Riya; Arvind Mishra; Karunakaran S. Anilkumar; Chandrasekharan K. Chandrakanth; Akhilesh K. Tamrakar; Arvind K. Srivastava; K. Gopalan Raghu

doi:10.1371/journal.pone.0105829

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Peer-reviewed

Research Article

Antidiabetic Property of Symplocos cochinchinensis Is Mediated by Inhibition of Alpha Glucosidase and Enhanced Insulin Sensitivity

Kalathookunnel Antony Antu,

Affiliation Agroprocessing and Natural Products Division, Council of Scientific and Industrial Research-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, Kerala, India
⨯
Mariam Philip Riya,

Affiliation Agroprocessing and Natural Products Division, Council of Scientific and Industrial Research-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, Kerala, India
⨯
Arvind Mishra,

Affiliation Division of Biochemistry, Council of Scientific and Industrial Research-Central Drug Research Institute (CSIR-CDRI), Lucknow, Uttar Pradesh, India
⨯
Karunakaran S. Anilkumar,

Affiliation Medicinal Chemistry Division, CSIR-CDRI, Lucknow, Uttar Pradesh, India
⨯
Chandrasekharan K. Chandrakanth,

Affiliation Agroprocessing and Natural Products Division, Council of Scientific and Industrial Research-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, Kerala, India
⨯
Akhilesh K. Tamrakar,

Affiliation Division of Pharmacology, CSIR-CDRI, Lucknow, Uttar Pradesh, India
⨯
Arvind K. Srivastava,

Affiliation Division of Biochemistry, Council of Scientific and Industrial Research-Central Drug Research Institute (CSIR-CDRI), Lucknow, Uttar Pradesh, India
⨯
K. Gopalan Raghu

* E-mail: raghukgopal2009@rediffmail.com

Affiliation Agroprocessing and Natural Products Division, Council of Scientific and Industrial Research-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, Kerala, India
⨯

Antidiabetic Property of Symplocos cochinchinensis Is Mediated by Inhibition of Alpha Glucosidase and Enhanced Insulin Sensitivity

Kalathookunnel Antony Antu,
Mariam Philip Riya,
Arvind Mishra,
Karunakaran S. Anilkumar,
Chandrasekharan K. Chandrakanth,
Akhilesh K. Tamrakar,
Arvind K. Srivastava,
K. Gopalan Raghu

Published: September 3, 2014
https://doi.org/10.1371/journal.pone.0105829

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