Development of a One-Step Probe Based Molecular Assay for Rapid Immunodiagnosis of Infection with M. tuberculosis Using Dried Blood Spots

Thomas Blauenfeldt; Jan Heyckendorf; Sidse Graff Jensen; Christoph Lange; Camilla Drabe; Thomas S. Hermansen; Lena de Thurah; Troels Lillebaek; Jesper Eugen-Olsen; Niels Seersholm; Søren Hoff; Jesper Bonde; Morten Ruhwald

doi:10.1371/journal.pone.0105628

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Open Access

Peer-reviewed

Research Article

Development of a One-Step Probe Based Molecular Assay for Rapid Immunodiagnosis of Infection with M. tuberculosis Using Dried Blood Spots

Thomas Blauenfeldt,

Affiliations Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark, Clinical Research Centre, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark
⨯
Jan Heyckendorf,

Affiliation Clinical Infectious Diseases, German Center for Infection Research (DZIF) Tuberculosis Unit, Research Center Borstel, Borstel, Germany
⨯
Sidse Graff Jensen,

Affiliation Department of Pulmonary Medicine, Copenhagen University Hospital Gentofte, Copenhagen, Denmark
⨯
Christoph Lange,

Affiliations Clinical Infectious Diseases, German Center for Infection Research (DZIF) Tuberculosis Unit, Research Center Borstel, Borstel, Germany, Department of Medicine, University of Namibia School of Medicine, Windhoek, Namibia
⨯
Camilla Drabe,

Affiliation Clinical Research Centre, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark
⨯
Thomas S. Hermansen,

Affiliation International Reference Laboratory of Mycobacteriology, Statens Serum Institut, Copenhagen, Denmark
⨯
Lena de Thurah,

Affiliations Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark, Clinical Research Centre, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark
⨯
Troels Lillebaek,

Affiliation International Reference Laboratory of Mycobacteriology, Statens Serum Institut, Copenhagen, Denmark
⨯
Jesper Eugen-Olsen,

Affiliation Clinical Research Centre, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark
⨯
Niels Seersholm,

Affiliation Department of Pulmonary Medicine, Copenhagen University Hospital Gentofte, Copenhagen, Denmark
⨯
Søren Hoff,

Affiliation Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark
⨯
Jesper Bonde,

Affiliations Clinical Research Centre, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark, Department of Pathology, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark
⨯
Morten Ruhwald

* E-mail: moru@ssi.dk

Affiliations Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark, Clinical Research Centre, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark
⨯

Development of a One-Step Probe Based Molecular Assay for Rapid Immunodiagnosis of Infection with M. tuberculosis Using Dried Blood Spots

Thomas Blauenfeldt,
Jan Heyckendorf,
Sidse Graff Jensen,
Christoph Lange,
Camilla Drabe,
Thomas S. Hermansen,
Lena de Thurah,
Troels Lillebaek,
Jesper Eugen-Olsen,
Niels Seersholm

Published: September 3, 2014
https://doi.org/10.1371/journal.pone.0105628

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