A Novel MicroRNA-132-Surtuin-1 Axis Underlies Aberrant B-cell Cytokine Regulation in Patients with Relapsing-Remitting Multiple Sclerosis

• Yusei Miyazaki,

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Rui Li ,

  Contributed equally to this work with: Rui Li, Ayman Rezk

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Ayman Rezk ,

  Contributed equally to this work with: Rui Li, Ayman Rezk

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Hétoum Misirliyan,

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Craig Moore,

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Nasr Farooqi,

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Mayra Solis,

  Affiliation Clinical Research Unit, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Lorna Galleguillos Goiry,

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Omar de Faria Junior,

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Van Duc Dang,

  Affiliation Deutsches Rheuma-Forschungszentrum, Leibniz Institute, Berlin, Germany

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• David Colman,

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Ajit Singh Dhaunchak,

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Jack Antel,

  Affiliation Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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• Jennifer Gommerman,

  Affiliation Department of Immunology, University of Toronto, Toronto, Ontario, Canada

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• Alexandre Prat,

  Affiliation Neuroimmunology Research Unit, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada

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• Simon Fillatreau,

  Affiliation Deutsches Rheuma-Forschungszentrum, Leibniz Institute, Berlin, Germany

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• Amit Bar-Or ,

  * E-mail: amit.bar-or@mcgill.ca

  Affiliations Neuroimmunology Unit and Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada, Clinical Research Unit, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada, Experimental Therapeutics Program, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada

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•  [ ... ],
• on behalf of the CIHR/MSSC New Emerging Team Grant in Clinical Autoimmunity and the MSSRF Canadian B cells in MS Team
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