Inhibition of c-Myc Overcomes Cytotoxic Drug Resistance in Acute Myeloid Leukemia Cells by Promoting Differentiation

Xiao-Na Pan; Jia-Jie Chen; Le-Xun Wang; Ruo-Zhi Xiao; Ling-Ling Liu; Zhi-Gang Fang; Quentin Liu; Zi-Jie Long; Dong-Jun Lin

doi:10.1371/journal.pone.0105381

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Open Access

Peer-reviewed

Research Article

Inhibition of c-Myc Overcomes Cytotoxic Drug Resistance in Acute Myeloid Leukemia Cells by Promoting Differentiation

Xiao-Na Pan ,

Contributed equally to this work with: Xiao-Na Pan, Jia-Jie Chen

Affiliations Department of Hematology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Sun Yat-sen Institute of Hematology, Sun Yat-sen University, Guangzhou, China
⨯
Jia-Jie Chen ,

Contributed equally to this work with: Xiao-Na Pan, Jia-Jie Chen

Affiliations Department of Hematology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Sun Yat-sen Institute of Hematology, Sun Yat-sen University, Guangzhou, China
⨯
Le-Xun Wang,

Affiliations Department of Hematology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Sun Yat-sen Institute of Hematology, Sun Yat-sen University, Guangzhou, China
⨯
Ruo-Zhi Xiao,

Affiliations Department of Hematology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Sun Yat-sen Institute of Hematology, Sun Yat-sen University, Guangzhou, China
⨯
Ling-Ling Liu,

Affiliations Department of Hematology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Sun Yat-sen Institute of Hematology, Sun Yat-sen University, Guangzhou, China
⨯
Zhi-Gang Fang,

Affiliations Department of Hematology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Sun Yat-sen Institute of Hematology, Sun Yat-sen University, Guangzhou, China
⨯
Quentin Liu,

Affiliations Department of Hematology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Sun Yat-sen Institute of Hematology, Sun Yat-sen University, Guangzhou, China
⨯
Zi-Jie Long ,

* E-mail: longzij@mail.sysu.edu.cn (ZL); lindj@mail.sysu.edu.cn (DL)

Affiliations Department of Hematology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Sun Yat-sen Institute of Hematology, Sun Yat-sen University, Guangzhou, China
⨯
Dong-Jun Lin

* E-mail: longzij@mail.sysu.edu.cn (ZL); lindj@mail.sysu.edu.cn (DL)

Affiliations Department of Hematology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Sun Yat-sen Institute of Hematology, Sun Yat-sen University, Guangzhou, China
⨯

Inhibition of c-Myc Overcomes Cytotoxic Drug Resistance in Acute Myeloid Leukemia Cells by Promoting Differentiation

Xiao-Na Pan,
Jia-Jie Chen,
Le-Xun Wang,
Ruo-Zhi Xiao,
Ling-Ling Liu,
Zhi-Gang Fang,
Quentin Liu,
Zi-Jie Long,
Dong-Jun Lin

Published: August 15, 2014
https://doi.org/10.1371/journal.pone.0105381

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