In Situ Characterization of Intrahepatic Non-Parenchymal Cells in PSC Reveals Phenotypic Patterns Associated with Disease Severity

Lena Berglin; Annika Bergquist; Helene Johansson; Hans Glaumann; Carl Jorns; Sebastian Lunemann; Heiner Wedemeyer; Ewa C. Ellis; Niklas K. Björkström

doi:10.1371/journal.pone.0105375

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Peer-reviewed

Research Article

In Situ Characterization of Intrahepatic Non-Parenchymal Cells in PSC Reveals Phenotypic Patterns Associated with Disease Severity

Lena Berglin,

Affiliation Liver Immunology Laboratory, Unit of Gastroenterology and Hepatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
⨯
Annika Bergquist,

Affiliation Liver Immunology Laboratory, Unit of Gastroenterology and Hepatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
⨯
Helene Johansson,

Affiliation Division of Transplantation Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
⨯
Hans Glaumann,

Affiliation Department of Medicine, Clinical Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden
⨯
Carl Jorns,

Affiliation Division of Transplantation Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
⨯
Sebastian Lunemann,

Affiliation Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
⨯
Heiner Wedemeyer,

Affiliation Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
⨯
Ewa C. Ellis,

Affiliation Division of Transplantation Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
⨯
Niklas K. Björkström

* E-mail: niklas.bjorkstrom@ki.se

Affiliations Liver Immunology Laboratory, Unit of Gastroenterology and Hepatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden, Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
⨯

In Situ Characterization of Intrahepatic Non-Parenchymal Cells in PSC Reveals Phenotypic Patterns Associated with Disease Severity

Lena Berglin,
Annika Bergquist,
Helene Johansson,
Hans Glaumann,
Carl Jorns,
Sebastian Lunemann,
Heiner Wedemeyer,
Ewa C. Ellis,
Niklas K. Björkström

Published: August 20, 2014
https://doi.org/10.1371/journal.pone.0105375

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