Glycoconjugate Vaccine Containing Escherichia coli O157:H7 O-Antigen Linked with Maltose-Binding Protein Elicits Humoral and Cellular Responses

Zhongrui Ma; Huajie Zhang; Wenjing Shang; Faliang Zhu; Weiqing Han; Xueer Zhao; Donglei Han; Peng George Wang; Min Chen

doi:10.1371/journal.pone.0105215

Loading metrics

Open Access

Peer-reviewed

Research Article

Glycoconjugate Vaccine Containing Escherichia coli O157:H7 O-Antigen Linked with Maltose-Binding Protein Elicits Humoral and Cellular Responses

Zhongrui Ma,

Affiliation School of Life Sciences and The State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, Shandong University, Jinan, Shandong, China
⨯
Huajie Zhang,

Affiliation School of Life Sciences and The State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, Shandong University, Jinan, Shandong, China
⨯
Wenjing Shang,

Affiliation Department of Biochemistry and Molecular Biology, Binzhou Medical University, YanTai, Shandong, China
⨯
Faliang Zhu,

Affiliation Department of Immunology, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Weiqing Han,

Affiliation College of Pharmacy and the State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
⨯
Xueer Zhao,

Affiliation School of Life Sciences and The State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, Shandong University, Jinan, Shandong, China
⨯
Donglei Han,

Affiliation School of Life Sciences and The State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, Shandong University, Jinan, Shandong, China
⨯
Peng George Wang,

Affiliation School of Life Sciences and The State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, Shandong University, Jinan, Shandong, China
⨯
Min Chen

* E-mail: chenmin@sdu.edu.cn

Affiliation School of Life Sciences and The State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, Shandong University, Jinan, Shandong, China
⨯

Glycoconjugate Vaccine Containing Escherichia coli O157:H7 O-Antigen Linked with Maltose-Binding Protein Elicits Humoral and Cellular Responses

Zhongrui Ma,
Huajie Zhang,
Wenjing Shang,
Faliang Zhu,
Weiqing Han,
Xueer Zhao,
Donglei Han,
Peng George Wang,
Min Chen

Published: August 19, 2014
https://doi.org/10.1371/journal.pone.0105215

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Enzyme-linked immunoassays
Is the Subject Area "Enzyme-linked immunoassays" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Vaccines
Is the Subject Area "Vaccines" applicable to this article?

Thanks for your feedback.
Bacterial pathogens
Is the Subject Area "Bacterial pathogens" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Escherichia coli
Is the Subject Area "Escherichia coli" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.