Transferred BCR/ABL DNA from K562 Extracellular Vesicles Causes Chronic Myeloid Leukemia in Immunodeficient Mice

Jin Cai; Gengze Wu; Xiaorong Tan; Yu Han; Caiyu Chen; Chuanwei Li; Na Wang; Xue Zou; Xinjian Chen; Faying Zhou; Duofen He; Lin Zhou; Pedro A. Jose; Chunyu Zeng

doi:10.1371/journal.pone.0105200

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Open Access

Peer-reviewed

Research Article

Transferred BCR/ABL DNA from K562 Extracellular Vesicles Causes Chronic Myeloid Leukemia in Immunodeficient Mice

Jin Cai ,

Contributed equally to this work with: Jin Cai, Gengze Wu, Xiaorong Tan

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Clinic of Health Service, Logistics Department, Air Force of Nanjing Area Command, Nanjing, Jiangsu, P.R. China
⨯
Gengze Wu ,

Contributed equally to this work with: Jin Cai, Gengze Wu, Xiaorong Tan

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Xiaorong Tan ,

Contributed equally to this work with: Jin Cai, Gengze Wu, Xiaorong Tan

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Yu Han,

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Caiyu Chen,

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Chuanwei Li,

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Na Wang,

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Xue Zou,

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Xinjian Chen,

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Faying Zhou,

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Duofen He,

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Lin Zhou,

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯
Pedro A. Jose,

Affiliation Division of Nephrology, Departments of Medicine and Physiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯
Chunyu Zeng

* E-mail: chunyuzeng01@163.com

Affiliation Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China
⨯

Transferred BCR/ABL DNA from K562 Extracellular Vesicles Causes Chronic Myeloid Leukemia in Immunodeficient Mice

Jin Cai,
Gengze Wu,
Xiaorong Tan,
Yu Han,
Caiyu Chen,
Chuanwei Li,
Na Wang,
Xue Zou,
Xinjian Chen,
Faying Zhou

Published: August 18, 2014
https://doi.org/10.1371/journal.pone.0105200

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