Increased Expression of CCN2, Epithelial Membrane Antigen, and Fibroblast Activation Protein in Hepatocellular Carcinoma with Fibrous Stroma Showing Aggressive Behavior

Gi Jeong Kim; Hyungjin Rhee; Jeong Eun Yoo; Jung Eun Ko; Jee San Lee; Hyunki Kim; Jin Sub Choi; Young Nyun Park

doi:10.1371/journal.pone.0105094

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Peer-reviewed

Research Article

Increased Expression of CCN2, Epithelial Membrane Antigen, and Fibroblast Activation Protein in Hepatocellular Carcinoma with Fibrous Stroma Showing Aggressive Behavior

Gi Jeong Kim ,

Contributed equally to this work with: Gi Jeong Kim, Hyungjin Rhee

Affiliation Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Hyungjin Rhee ,

Contributed equally to this work with: Gi Jeong Kim, Hyungjin Rhee

Affiliations Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea, BK21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Jeong Eun Yoo,

Affiliation Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Jung Eun Ko,

Affiliations Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea, BK21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Jee San Lee,

Affiliations Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea, BK21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Hyunki Kim,

Affiliation Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Jin Sub Choi,

Affiliation Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Young Nyun Park

* E-mail: young0608@yuhs.ac

Affiliations Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea, Integrated Genomic Research Center for Metabolic Regulation, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯

Increased Expression of CCN2, Epithelial Membrane Antigen, and Fibroblast Activation Protein in Hepatocellular Carcinoma with Fibrous Stroma Showing Aggressive Behavior

Gi Jeong Kim,
Hyungjin Rhee,
Jeong Eun Yoo,
Jung Eun Ko,
Jee San Lee,
Hyunki Kim,
Jin Sub Choi,
Young Nyun Park

Published: August 15, 2014
https://doi.org/10.1371/journal.pone.0105094

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Hepatocellular carcinoma
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Lung and intrathoracic tumors
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Fibroblasts
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Epithelial cells
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