Impact of Hormone-Associated Resistance to Activated Protein C on the Thrombotic Potential of Oral Contraceptives: A Prospective Observational Study

Heiko Rühl; Lars Schröder; Jens Müller; Shorena Sukhitashvili; Julia Welz; Walther C. Kuhn; Johannes Oldenburg; Christian Rudlowski; Bernd Pötzsch

doi:10.1371/journal.pone.0105007

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Peer-reviewed

Research Article

Impact of Hormone-Associated Resistance to Activated Protein C on the Thrombotic Potential of Oral Contraceptives: A Prospective Observational Study

Heiko Rühl ,

Contributed equally to this work with: Heiko Rühl, Lars Schröder

* E-mail: heiko.ruehl@ukb.uni-bonn.de

Affiliation Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany
⨯
Lars Schröder ,

Contributed equally to this work with: Heiko Rühl, Lars Schröder

Affiliation Department of Gynecology and Obstetrics, Center for Integrated Oncology (CIO) Köln/Bonn, University Hospital Bonn, Bonn, Germany
⨯
Jens Müller,

Affiliation Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany
⨯
Shorena Sukhitashvili,

Affiliation Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany
⨯
Julia Welz,

Affiliations Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany, Department of Gynecology and Obstetrics, Center for Integrated Oncology (CIO) Köln/Bonn, University Hospital Bonn, Bonn, Germany
⨯
Walther C. Kuhn,

Affiliation Department of Gynecology and Obstetrics, Center for Integrated Oncology (CIO) Köln/Bonn, University Hospital Bonn, Bonn, Germany
⨯
Johannes Oldenburg,

Affiliation Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany
⨯
Christian Rudlowski,

Affiliation Department of Gynecology and Obstetrics, Center for Integrated Oncology (CIO) Köln/Bonn, University Hospital Bonn, Bonn, Germany
⨯
Bernd Pötzsch

Affiliation Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany
⨯

Impact of Hormone-Associated Resistance to Activated Protein C on the Thrombotic Potential of Oral Contraceptives: A Prospective Observational Study

Heiko Rühl,
Lars Schröder,
Jens Müller,
Shorena Sukhitashvili,
Julia Welz,
Walther C. Kuhn,
Johannes Oldenburg,
Christian Rudlowski,
Bernd Pötzsch

Published: August 14, 2014
https://doi.org/10.1371/journal.pone.0105007

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