In-Cell Intrabody Selection from a Diverse Human Library Identifies C12orf4 Protein as a New Player in Rodent Mast Cell Degranulation

Elsa Mazuc; Laurence Guglielmi; Nicole Bec; Vincent Parez; Chang S. Hahn; Caroline Mollevi; Hugues Parrinello; Jean-Pierre Desvignes; Christian Larroque; Ray Jupp; Piona Dariavach; Pierre Martineau

doi:10.1371/journal.pone.0104998

Loading metrics

Open Access

Peer-reviewed

Research Article

In-Cell Intrabody Selection from a Diverse Human Library Identifies C12orf4 Protein as a New Player in Rodent Mast Cell Degranulation

Elsa Mazuc ,

Contributed equally to this work with: Elsa Mazuc, Laurence Guglielmi

Affiliations IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, INSERM, U896, Montpellier, France, Université Montpellier1, Montpellier, France, ICM, Institut régional du Cancer Montpellier, Montpellier, France
⨯
Laurence Guglielmi ,

Contributed equally to this work with: Elsa Mazuc, Laurence Guglielmi

Affiliations IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, INSERM, U896, Montpellier, France, Université Montpellier1, Montpellier, France, ICM, Institut régional du Cancer Montpellier, Montpellier, France
⨯
Nicole Bec,

Affiliations IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, INSERM, U896, Montpellier, France, Université Montpellier1, Montpellier, France, ICM, Institut régional du Cancer Montpellier, Montpellier, France
⨯
Vincent Parez,

Affiliations IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, INSERM, U896, Montpellier, France, Université Montpellier1, Montpellier, France, ICM, Institut régional du Cancer Montpellier, Montpellier, France
⨯
Chang S. Hahn,

Affiliation Sanofi-Aventis, Bridgewater, New Jersey, United States of America
⨯
Caroline Mollevi,

Affiliation ICM, Institut régional du Cancer Montpellier, Montpellier, France
⨯
Hugues Parrinello,

Affiliation MGX-Montpellier GenomiX, Institut de Génomique Fonctionnelle, Montpellier, France
⨯
Jean-Pierre Desvignes,

Affiliation MGX-Montpellier GenomiX, Institut de Génomique Fonctionnelle, Montpellier, France
⨯
Christian Larroque,

Affiliations IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, INSERM, U896, Montpellier, France, Université Montpellier1, Montpellier, France, ICM, Institut régional du Cancer Montpellier, Montpellier, France
⨯
Ray Jupp,

Affiliation Sanofi-Aventis, Bridgewater, New Jersey, United States of America
⨯
Piona Dariavach ,

* E-mail: piona.dariavach@inserm.fr (PD); pierre.martineau@inserm.fr (PM)

¶These authors also contributed equally to this work.

Affiliations IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, INSERM, U896, Montpellier, France, Université Montpellier1, Montpellier, France, ICM, Institut régional du Cancer Montpellier, Montpellier, France, Université Montpellier2, Montpellier, France
⨯
Pierre Martineau

* E-mail: piona.dariavach@inserm.fr (PD); pierre.martineau@inserm.fr (PM)

¶These authors also contributed equally to this work.

Affiliations IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, INSERM, U896, Montpellier, France, Université Montpellier1, Montpellier, France, ICM, Institut régional du Cancer Montpellier, Montpellier, France
⨯

In-Cell Intrabody Selection from a Diverse Human Library Identifies C12orf4 Protein as a New Player in Rodent Mast Cell Degranulation

Elsa Mazuc,
Laurence Guglielmi,
Nicole Bec,
Vincent Parez,
Chang S. Hahn,
Caroline Mollevi,
Hugues Parrinello,
Jean-Pierre Desvignes,
Christian Larroque,
Ray Jupp

Published: August 14, 2014
https://doi.org/10.1371/journal.pone.0104998

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Cell degranulation
Is the Subject Area "Cell degranulation" applicable to this article?

Thanks for your feedback.
Mast cells
Is the Subject Area "Mast cells" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Allergies
Is the Subject Area "Allergies" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.
Secretion
Is the Subject Area "Secretion" applicable to this article?

Thanks for your feedback.
Tyrosine kinases
Is the Subject Area "Tyrosine kinases" applicable to this article?

Thanks for your feedback.