Self-Assembly and Release of Peste des Petits Ruminants Virus-Like Particles in an Insect Cell-Baculovirus System and Their Immunogenicity in Mice and Goats

Wenchao Li; Hongyan Jin; Xiukun Sui; Zhanzhong Zhao; Chenghuai Yang; Wenquan Wang; Junping Li; Gang Li

doi:10.1371/journal.pone.0104791

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Open Access

Peer-reviewed

Research Article

Self-Assembly and Release of Peste des Petits Ruminants Virus-Like Particles in an Insect Cell-Baculovirus System and Their Immunogenicity in Mice and Goats

Wenchao Li,

Affiliations State Key Laboratory of Animal Nutrition, Beijing Institute of Animal Science and Veterinary Medicine, Chinese Academy of Agricultural Sciences; Beijing Scientific Observation and Experiment Station for Veterinary Drug and Veterinary Biotechnology, Ministry of Agriculture, Beijing, PR China, Beijing CevaHuadu Biological Co., Ltd, Beijing, PR China
⨯
Hongyan Jin,

Affiliation State Key Laboratory of Animal Nutrition, Beijing Institute of Animal Science and Veterinary Medicine, Chinese Academy of Agricultural Sciences; Beijing Scientific Observation and Experiment Station for Veterinary Drug and Veterinary Biotechnology, Ministry of Agriculture, Beijing, PR China
⨯
Xiukun Sui,

Affiliation State Key Laboratory of Animal Nutrition, Beijing Institute of Animal Science and Veterinary Medicine, Chinese Academy of Agricultural Sciences; Beijing Scientific Observation and Experiment Station for Veterinary Drug and Veterinary Biotechnology, Ministry of Agriculture, Beijing, PR China
⨯
Zhanzhong Zhao,

Affiliation State Key Laboratory of Animal Nutrition, Beijing Institute of Animal Science and Veterinary Medicine, Chinese Academy of Agricultural Sciences; Beijing Scientific Observation and Experiment Station for Veterinary Drug and Veterinary Biotechnology, Ministry of Agriculture, Beijing, PR China
⨯
Chenghuai Yang,

Affiliation China Institute of Veterinary Drug Control, Beijing, PR China
⨯
Wenquan Wang,

Affiliation Beijing CevaHuadu Biological Co., Ltd, Beijing, PR China
⨯
Junping Li ,

* E-mail: gli358@gmail.com (GL); lijunping03@163.com (JL)

Affiliation China Institute of Veterinary Drug Control, Beijing, PR China
⨯
Gang Li

* E-mail: gli358@gmail.com (GL); lijunping03@163.com (JL)

Affiliation State Key Laboratory of Animal Nutrition, Beijing Institute of Animal Science and Veterinary Medicine, Chinese Academy of Agricultural Sciences; Beijing Scientific Observation and Experiment Station for Veterinary Drug and Veterinary Biotechnology, Ministry of Agriculture, Beijing, PR China
⨯

Self-Assembly and Release of Peste des Petits Ruminants Virus-Like Particles in an Insect Cell-Baculovirus System and Their Immunogenicity in Mice and Goats

Wenchao Li,
Hongyan Jin,
Xiukun Sui,
Zhanzhong Zhao,
Chenghuai Yang,
Wenquan Wang,
Junping Li,
Gang Li

Published: August 12, 2014
https://doi.org/10.1371/journal.pone.0104791

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