Anti-Peroxynitrite Treatment Ameliorated Vasorelaxation of Resistance Arteries in Aging Rats: Involvement with NO-sGC-cGKs Pathway

Lu Ma; Ke Wang; Jianyu Shang; Chengzhang Cao; Panpan Zhen; Xin Liu; Wen Wang; Hui Zhang; Yunhui Du; Huirong Liu

doi:10.1371/journal.pone.0104788

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Open Access

Peer-reviewed

Research Article

Anti-Peroxynitrite Treatment Ameliorated Vasorelaxation of Resistance Arteries in Aging Rats: Involvement with NO-sGC-cGKs Pathway

Lu Ma,

Affiliation Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, PR China
⨯
Ke Wang,

Affiliation Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, PR China
⨯
Jianyu Shang,

Affiliation Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, PR China
⨯
Chengzhang Cao,

Affiliation Department of Chest Surgery, First Hospital of Longyan, Fujian Medical University, Fujian, PR China
⨯
Panpan Zhen,

Affiliation Department of Pathology, Luhe Hospital, Capital Medical University, Beijing, PR China
⨯
Xin Liu,

Affiliation Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, PR China
⨯
Wen Wang,

Affiliation Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, PR China
⨯
Hui Zhang,

Affiliation Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, PR China
⨯
Yunhui Du,

Affiliation Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, PR China
⨯
Huirong Liu

* E-mail: liuhr2000@126.com

Affiliations Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, PR China, Beijing Key Laboratory of Metabolic Disturbance Related Cardiovascular Disease, Beijing, PR China
⨯

Anti-Peroxynitrite Treatment Ameliorated Vasorelaxation of Resistance Arteries in Aging Rats: Involvement with NO-sGC-cGKs Pathway

Lu Ma,
Ke Wang,
Jianyu Shang,
Chengzhang Cao,
Panpan Zhen,
Xin Liu,
Wen Wang,
Hui Zhang,
Yunhui Du,
Huirong Liu

Published: August 12, 2014
https://doi.org/10.1371/journal.pone.0104788

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cGMP signaling
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