NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

Beibei Luo; Bo Li; Wenke Wang; Xiangjuan Liu; Yanfei Xia; Cheng Zhang; Mingxiang Zhang; Yun Zhang; Fengshuang An

doi:10.1371/journal.pone.0104771

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Open Access

Peer-reviewed

Research Article

NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

Beibei Luo,

Affiliation The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China
⨯
Bo Li,

Affiliation The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China
⨯
Wenke Wang,

Affiliation The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China
⨯
Xiangjuan Liu,

Affiliation The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China
⨯
Yanfei Xia,

Affiliation The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China
⨯
Cheng Zhang,

Affiliation The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China
⨯
Mingxiang Zhang,

Affiliation The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China
⨯
Yun Zhang,

Affiliation The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China
⨯
Fengshuang An

* E-mail: anfengshuang@aliyun.com

Affiliation The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China
⨯

NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

Beibei Luo,
Bo Li,
Wenke Wang,
Xiangjuan Liu,
Yanfei Xia,
Cheng Zhang,
Mingxiang Zhang,
Yun Zhang,
Fengshuang An

Published: August 19, 2014
https://doi.org/10.1371/journal.pone.0104771

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Diabetes mellitus
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Gene silencing
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Cell death
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