Improving the Anti-Toxin Abilities of the CMG2-Fc Fusion Protein with the Aid of Computational Design

Open Access

Peer-reviewed

Research Article

Yongyi Xi ,

Contributed equally to this work with: Yongyi Xi, Xiaojie Wu, Lihua Gao, Yong Shao

Affiliation Beijing Institute of Biotechnology, Beijing, China
⨯
Xiaojie Wu ,

Contributed equally to this work with: Yongyi Xi, Xiaojie Wu, Lihua Gao, Yong Shao

Affiliation Beijing Institute of Biotechnology, Beijing, China
⨯
Lihua Gao ,

Contributed equally to this work with: Yongyi Xi, Xiaojie Wu, Lihua Gao, Yong Shao

Affiliation Beijing Institute of Biotechnology, Beijing, China
⨯
Yong Shao ,

Contributed equally to this work with: Yongyi Xi, Xiaojie Wu, Lihua Gao, Yong Shao

Affiliation Beijing Institute of Biotechnology, Beijing, China
⨯
Hui Peng,

Affiliation Beijing Institute of Biotechnology, Beijing, China
⨯
Hongxing Chen,

Affiliation Beijing Institute of Biotechnology, Beijing, China
⨯
Huipeng Chen ,

* E-mail: hpcamms@126.com (HPC); hu.xianwen@tsinghua.org.cn (XWH); yue_junjie@126.com (JJY)

Affiliation Beijing Institute of Biotechnology, Beijing, China
⨯
Xianwen Hu ,

* E-mail: hpcamms@126.com (HPC); hu.xianwen@tsinghua.org.cn (XWH); yue_junjie@126.com (JJY)

Affiliation Beijing Institute of Biotechnology, Beijing, China
⨯
Junjie Yue

* E-mail: hpcamms@126.com (HPC); hu.xianwen@tsinghua.org.cn (XWH); yue_junjie@126.com (JJY)

Affiliation Beijing Institute of Biotechnology, Beijing, China
⨯

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Toxins
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Substitution mutation
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CHO cells
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Crystal structure
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Cell binding assay
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