Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection

René H. M. Raeven; Jolanda Brummelman; Jeroen L. A. Pennings; Olaf E. M. Nijst; Betsy Kuipers; Laura E. R. Blok; Kina Helm; Elly van Riet; Wim Jiskoot; Cecile A. C. M. van Els; Wanda G. H. Han; Gideon F. A. Kersten; Bernard Metz

doi:10.1371/journal.pone.0104548

Loading metrics

Open Access

Peer-reviewed

Research Article

Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection

René H. M. Raeven ,

* E-mail: Rene.raeven@intravacc.nl

Affiliations Intravacc, Bilthoven, The Netherlands, Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands
⨯
Jolanda Brummelman,

Affiliation Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Jeroen L. A. Pennings,

Affiliation Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Olaf E. M. Nijst,

Affiliation Intravacc, Bilthoven, The Netherlands
⨯
Betsy Kuipers,

Affiliation Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Laura E. R. Blok,

Affiliation Intravacc, Bilthoven, The Netherlands
⨯
Kina Helm,

Affiliation Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Elly van Riet,

Affiliation Intravacc, Bilthoven, The Netherlands
⨯
Wim Jiskoot,

Affiliation Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands
⨯
Cecile A. C. M. van Els,

Affiliation Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Wanda G. H. Han,

Affiliation Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
⨯
Gideon F. A. Kersten,

Affiliations Intravacc, Bilthoven, The Netherlands, Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands
⨯
Bernard Metz

Affiliation Intravacc, Bilthoven, The Netherlands
⨯

Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection

René H. M. Raeven,
Jolanda Brummelman,
Jeroen L. A. Pennings,
Olaf E. M. Nijst,
Betsy Kuipers,
Laura E. R. Blok,
Kina Helm,
Elly van Riet,
Wim Jiskoot,
Cecile A. C. M. van Els

Published: August 19, 2014
https://doi.org/10.1371/journal.pone.0104548

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Bordetella pertussis
Is the Subject Area "Bordetella pertussis" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Spleen
Is the Subject Area "Spleen" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
B cells
Is the Subject Area "B cells" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.