Characterization of Nodal/TGF-Lefty Signaling Pathway Gene Variants for Possible Roles in Congenital Heart Diseases

Xia Deng; Jing Zhou; Fei-Feng Li; Peng Yan; Er-Ying Zhao; Ling Hao; Kai-Jiang Yu; Shu-Lin Liu

doi:10.1371/journal.pone.0104535

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Open Access

Peer-reviewed

Research Article

Characterization of Nodal/TGF-Lefty Signaling Pathway Gene Variants for Possible Roles in Congenital Heart Diseases

Xia Deng ,

Contributed equally to this work with: Xia Deng, Jing Zhou

Affiliation Genomics Research Center (one of the State-Province Key Laboratory of Biopharmaceutical Engineering, China), Harbin Medical University, Harbin, China
⨯
Jing Zhou ,

Contributed equally to this work with: Xia Deng, Jing Zhou

Affiliation Intensive Care Unit, the Second Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Fei-Feng Li ,

* E-mail: drkaijiang@163.com (K-JY); lff-1981@163.com (F-FL); slliu@ucalgary.ca (S-LL)

Affiliation Genomics Research Center (one of the State-Province Key Laboratory of Biopharmaceutical Engineering, China), Harbin Medical University, Harbin, China
⨯
Peng Yan,

Affiliation Department of Colorectal Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Er-Ying Zhao,

Affiliation Genomics Research Center (one of the State-Province Key Laboratory of Biopharmaceutical Engineering, China), Harbin Medical University, Harbin, China
⨯
Ling Hao,

Affiliation Department of Oncology, the Fourth Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Kai-Jiang Yu ,

* E-mail: drkaijiang@163.com (K-JY); lff-1981@163.com (F-FL); slliu@ucalgary.ca (S-LL)

Affiliation Intensive Care Unit, the Second Affiliated Hospital of Harbin Medical University, Harbin, China
⨯
Shu-Lin Liu

* E-mail: drkaijiang@163.com (K-JY); lff-1981@163.com (F-FL); slliu@ucalgary.ca (S-LL)

Affiliations Genomics Research Center (one of the State-Province Key Laboratory of Biopharmaceutical Engineering, China), Harbin Medical University, Harbin, China, Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Canada
⨯

Characterization of Nodal/TGF-Lefty Signaling Pathway Gene Variants for Possible Roles in Congenital Heart Diseases

Xia Deng,
Jing Zhou,
Fei-Feng Li,
Peng Yan,
Er-Ying Zhao,
Ling Hao,
Kai-Jiang Yu,
Shu-Lin Liu

Published: August 11, 2014
https://doi.org/10.1371/journal.pone.0104535

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Variant genotypes
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Single nucleotide polymorphisms
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