A Yersinia pestis tat Mutant Is Attenuated in Bubonic and Small-Aerosol Pneumonic Challenge Models of Infection but Not As Attenuated by Intranasal Challenge

Joel Bozue; Christopher K. Cote; Taylor Chance; Jeffrey Kugelman; Steven J. Kern; Todd K. Kijek; Amy Jenkins; Sherry Mou; Krishna Moody; David Fritz; Camenzind G. Robinson; Todd Bell; Patricia Worsham

doi:10.1371/journal.pone.0104524

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Peer-reviewed

Research Article

A Yersinia pestis tat Mutant Is Attenuated in Bubonic and Small-Aerosol Pneumonic Challenge Models of Infection but Not As Attenuated by Intranasal Challenge

Joel Bozue ,

* E-mail: joel.a.bozue@us.army.mil

Affiliation Bacteriology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Christopher K. Cote,

Affiliation Bacteriology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Taylor Chance,

Affiliation Pathology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Jeffrey Kugelman,

Affiliation Center for Genome Sciences, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Steven J. Kern,

Affiliation Office of Research Support, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Todd K. Kijek,

Affiliation Bacteriology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Amy Jenkins,

Affiliation Bacteriology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Sherry Mou,

Affiliation Bacteriology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Krishna Moody,

Affiliation Bacteriology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
David Fritz,

Affiliation Bacteriology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Camenzind G. Robinson,

Affiliation Pathology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Todd Bell,

Affiliation Pathology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Patricia Worsham

Affiliation Bacteriology Division, The United States Army of Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯

A Yersinia pestis tat Mutant Is Attenuated in Bubonic and Small-Aerosol Pneumonic Challenge Models of Infection but Not As Attenuated by Intranasal Challenge

Joel Bozue,
Christopher K. Cote,
Taylor Chance,
Jeffrey Kugelman,
Steven J. Kern,
Todd K. Kijek,
Amy Jenkins,
Sherry Mou,
Krishna Moody,
David Fritz

Published: August 7, 2014
https://doi.org/10.1371/journal.pone.0104524

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