PI3K/Akt Signaling Pathway Modulates Influenza Virus Induced Mouse Alveolar Macrophage Polarization to M1/M2b

Xiangfeng Zhao; Jianping Dai; Xuejun Xiao; Liqi Wu; Jun Zeng; Jiangtao Sheng; Jinghua Su; Xiaoxuan Chen; Gefei Wang; Kangsheng Li

doi:10.1371/journal.pone.0104506

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Peer-reviewed

Research Article

PI3K/Akt Signaling Pathway Modulates Influenza Virus Induced Mouse Alveolar Macrophage Polarization to M1/M2b

Xiangfeng Zhao,

Affiliation Department of Microbiology and Immunology, Shantou University Medical College, College, Shantou, Guangdong, China
⨯
Jianping Dai,

Affiliation Department of Microbiology and Immunology, Shantou University Medical College, College, Shantou, Guangdong, China
⨯
Xuejun Xiao,

Affiliation Department of Nursing, Guilin Medical University, Guilin, Guangxi, China
⨯
Liqi Wu,

Affiliation Department of Microbiology and Immunology, Shantou University Medical College, College, Shantou, Guangdong, China
⨯
Jun Zeng,

Affiliation Department of Microbiology and Immunology, Shantou University Medical College, College, Shantou, Guangdong, China
⨯
Jiangtao Sheng,

Affiliation Department of Microbiology and Immunology, Shantou University Medical College, College, Shantou, Guangdong, China
⨯
Jinghua Su,

Affiliation Department of Microbiology and Immunology, Shantou University Medical College, College, Shantou, Guangdong, China
⨯
Xiaoxuan Chen,

Affiliation Department of Microbiology and Immunology, Shantou University Medical College, College, Shantou, Guangdong, China
⨯
Gefei Wang ,

* E-mail: kslistuedu@sohu.com (KsL); silvermask007@163.com (GfW)

Affiliation Department of Microbiology and Immunology, Shantou University Medical College, College, Shantou, Guangdong, China
⨯
Kangsheng Li

* E-mail: kslistuedu@sohu.com (KsL); silvermask007@163.com (GfW)

Affiliation Department of Microbiology and Immunology, Shantou University Medical College, College, Shantou, Guangdong, China
⨯

PI3K/Akt Signaling Pathway Modulates Influenza Virus Induced Mouse Alveolar Macrophage Polarization to M1/M2b

Xiangfeng Zhao,
Jianping Dai,
Xuejun Xiao,
Liqi Wu,
Jun Zeng,
Jiangtao Sheng,
Jinghua Su,
Xiaoxuan Chen,
Gefei Wang,
Kangsheng Li

Published: August 8, 2014
https://doi.org/10.1371/journal.pone.0104506

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Influenza viruses
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Macrophages
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H1N1
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Alveolar macrophages
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Gene expression
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Toll-like receptors
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Enzyme-linked immunoassays
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