Early Biodistribution and Persistence of a Protective Live Attenuated SIV Vaccine Elicits Localised Innate Responses in Multiple Lymphoid Tissues

Deborah Ferguson; Giada Mattiuzzo; Claire Ham; Richard Stebbings; Bo Li; Nicola J. Rose; Edward T. Mee; Deborah Smith; Mark Page; Martin P. Cranage; Neil Almond; Greg J. Towers; Neil J. Berry

doi:10.1371/journal.pone.0104390

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Open Access

Peer-reviewed

Research Article

Early Biodistribution and Persistence of a Protective Live Attenuated SIV Vaccine Elicits Localised Innate Responses in Multiple Lymphoid Tissues

Deborah Ferguson ,

Contributed equally to this work with: Deborah Ferguson, Giada Mattiuzzo

Affiliation Division of Virology, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Giada Mattiuzzo ,

Contributed equally to this work with: Deborah Ferguson, Giada Mattiuzzo

Affiliation Division of Virology, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Claire Ham,

Affiliation Division of Virology, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Richard Stebbings,

Affiliation Division of Biotherapeutics, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Bo Li,

Affiliation Division of Biotherapeutics, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Nicola J. Rose,

Affiliation Division of Virology, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Edward T. Mee,

Affiliation Division of Virology, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Deborah Smith,

Affiliation Division of Virology, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Mark Page,

Affiliation Division of Virology, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Martin P. Cranage,

Affiliation Institute of Infection and Immunity, St. George's, University of London, London, United Kingdom
⨯
Neil Almond,

Affiliation Division of Virology, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯
Greg J. Towers ,

* E-mail: g.towers@ucl.ac.uk (GJT); neil.berry@nibsc.org (NB)

Affiliation MRC Centre of Medical Molecular Biology, Division of Infection and Immunity, UCL, London, United Kingdom
⨯
Neil J. Berry

* E-mail: g.towers@ucl.ac.uk (GJT); neil.berry@nibsc.org (NB)

Affiliation Division of Virology, NIBSC, South Mimms, Hertfordshire, United Kingdom
⨯

Early Biodistribution and Persistence of a Protective Live Attenuated SIV Vaccine Elicits Localised Innate Responses in Multiple Lymphoid Tissues

Deborah Ferguson,
Giada Mattiuzzo,
Claire Ham,
Richard Stebbings,
Bo Li,
Nicola J. Rose,
Edward T. Mee,
Deborah Smith,
Mark Page,
Martin P. Cranage

Published: August 27, 2014
https://doi.org/10.1371/journal.pone.0104390

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