Mutation Screening of Retinal Dystrophy Patients by Targeted Capture from Tagged Pooled DNAs and Next Generation Sequencing

Christopher M. Watson; Mohammed El-Asrag; David A. Parry; Joanne E. Morgan; Clare V. Logan; Ian M. Carr; Eamonn Sheridan; Ruth Charlton; Colin A. Johnson; Graham Taylor; Carmel Toomes; Martin McKibbin; Chris F. Inglehearn; Manir Ali

doi:10.1371/journal.pone.0104281

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Open Access

Peer-reviewed

Research Article

Mutation Screening of Retinal Dystrophy Patients by Targeted Capture from Tagged Pooled DNAs and Next Generation Sequencing

Christopher M. Watson ,

Contributed equally to this work with: Christopher M. Watson, Mohammed El-Asrag

Affiliation Yorkshire Regional Genetics Service, St. James's University Hospital, Leeds, United Kingdom
⨯
Mohammed El-Asrag ,

Contributed equally to this work with: Christopher M. Watson, Mohammed El-Asrag

Affiliation Section of Ophthalmology & Neuroscience, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯
David A. Parry,

Affiliation Section of Genetics, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯
Joanne E. Morgan,

Affiliation Section of Genetics, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯
Clare V. Logan,

Affiliation Section of Ophthalmology & Neuroscience, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯
Ian M. Carr,

Affiliation Section of Genetics, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯
Eamonn Sheridan,

Affiliation Section of Genetics, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯
Ruth Charlton,

Affiliation Yorkshire Regional Genetics Service, St. James's University Hospital, Leeds, United Kingdom
⨯
Colin A. Johnson,

Affiliation Section of Ophthalmology & Neuroscience, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯
Graham Taylor,

Affiliation Yorkshire Regional Genetics Service, St. James's University Hospital, Leeds, United Kingdom
⨯
Carmel Toomes,

Affiliation Section of Ophthalmology & Neuroscience, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯
Martin McKibbin,

Affiliations Section of Ophthalmology & Neuroscience, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom, Department of Ophthalmology, St. James's University Hospital, Leeds, United Kingdom
⨯
Chris F. Inglehearn,

Affiliation Section of Ophthalmology & Neuroscience, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯
Manir Ali

* E-mail: medma@leeds.ac.uk

Affiliation Section of Ophthalmology & Neuroscience, Leeds Institute of Biomedical & Clinical Sciences, University of Leeds, Leeds, United Kingdom
⨯

Mutation Screening of Retinal Dystrophy Patients by Targeted Capture from Tagged Pooled DNAs and Next Generation Sequencing

Christopher M. Watson,
Mohammed El-Asrag,
David A. Parry,
Joanne E. Morgan,
Clare V. Logan,
Ian M. Carr,
Eamonn Sheridan,
Ruth Charlton,
Colin A. Johnson,
Graham Taylor

Published: August 18, 2014
https://doi.org/10.1371/journal.pone.0104281

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