A Gene Panel, Including LRP12, Is Frequently Hypermethylated in Major Types of B-Cell Lymphoma

Nicole Bethge; Hilde Honne; Kim Andresen; Vera Hilden; Gunhild Trøen; Knut Liestøl; Harald Holte; Jan Delabie; Guro E. Lind; Erlend B. Smeland

doi:10.1371/journal.pone.0104249

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Peer-reviewed

Research Article

A Gene Panel, Including LRP12, Is Frequently Hypermethylated in Major Types of B-Cell Lymphoma

Nicole Bethge,

Affiliations Department of Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway
⨯
Hilde Honne,

Affiliations Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway, Department of Cancer Prevention, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
⨯
Kim Andresen,

Affiliations Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway, Department of Cancer Prevention, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
⨯
Vera Hilden,

Affiliations Department of Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway
⨯
Gunhild Trøen,

Affiliation Department of Pathology, Oslo University Hospital, Oslo, Norway
⨯
Knut Liestøl,

Affiliations Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway, Department of Informatics, University of Oslo, Oslo, Norway
⨯
Harald Holte,

Affiliations Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway, Department of Oncology, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
⨯
Jan Delabie,

Affiliation Department of Pathology, Oslo University Hospital, Oslo, Norway
⨯
Guro E. Lind,

Affiliations Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway, Department of Cancer Prevention, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
⨯
Erlend B. Smeland

* E-mail: ebs@rr-research.no

Affiliations Department of Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway
⨯

A Gene Panel, Including LRP12, Is Frequently Hypermethylated in Major Types of B-Cell Lymphoma

Nicole Bethge,
Hilde Honne,
Kim Andresen,
Vera Hilden,
Gunhild Trøen,
Knut Liestøl,
Harald Holte,
Jan Delabie,
Guro E. Lind,
Erlend B. Smeland

Published: September 16, 2014
https://doi.org/10.1371/journal.pone.0104249

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DNA methylation
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Lymphoma
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B cells
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Methylation
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Lymphoma cells
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Tumor suppressor genes
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Epigenetics
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Diffuse large B-cell lymphoma
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