An Interferon Response Gene Signature Is Associated with the Therapeutic Response of Hepatitis C Patients

Lawrence M. Pfeffer; Kui Li; Jaquelyn F. Fleckenstein; Tony N. Marion; Joel Diament; Chuan He Yang; Susan R. Pfeffer; Meiyun Fan; Elizabeth Handorf; Charles R. Handorf

doi:10.1371/journal.pone.0104202

Loading metrics

Open Access

Peer-reviewed

Research Article

An Interferon Response Gene Signature Is Associated with the Therapeutic Response of Hepatitis C Patients

Lawrence M. Pfeffer ,

* E-mail: LPFEFFER@UTHSC.EDU

Affiliation Department of Pathology and Laboratory Medicine, and the Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Kui Li,

Affiliation Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Jaquelyn F. Fleckenstein,

Affiliation The Department of Medicine, Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Tony N. Marion,

Affiliation Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Joel Diament,

Affiliation Department of Pathology and Laboratory Medicine, and the Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Chuan He Yang,

Affiliation Department of Pathology and Laboratory Medicine, and the Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Susan R. Pfeffer,

Affiliation Department of Pathology and Laboratory Medicine, and the Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Meiyun Fan,

Affiliation Department of Pathology and Laboratory Medicine, and the Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Elizabeth Handorf,

Affiliation Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
⨯
Charles R. Handorf

Affiliation Department of Pathology and Laboratory Medicine, and the Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯

An Interferon Response Gene Signature Is Associated with the Therapeutic Response of Hepatitis C Patients

Lawrence M. Pfeffer,
Kui Li,
Jaquelyn F. Fleckenstein,
Tony N. Marion,
Joel Diament,
Chuan He Yang,
Susan R. Pfeffer,
Meiyun Fan,
Elizabeth Handorf,
Charles R. Handorf

Published: August 11, 2014
https://doi.org/10.1371/journal.pone.0104202

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Hepatitis C virus
Is the Subject Area "Hepatitis C virus" applicable to this article?

Thanks for your feedback.
Interferons
Is the Subject Area "Interferons" applicable to this article?

Thanks for your feedback.
Biopsy
Is the Subject Area "Biopsy" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Viral gene expression
Is the Subject Area "Viral gene expression" applicable to this article?

Thanks for your feedback.
African American people
Is the Subject Area "African American people" applicable to this article?

Thanks for your feedback.
Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.