Metabolic Reprogramming towards Aerobic Glycolysis Correlates with Greater Proliferative Ability and Resistance to Metabolic Inhibition in CD8 versus CD4 T Cells

Open Access

Peer-reviewed

Research Article

Yilin Cao,

Affiliation Department of Pharmacology and Cancer Biology, Department of Immunology, Sarah W. Stedman Center for Nutrition and Metabolism, Duke University, Durham, NC, United States of America
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Jeffrey C. Rathmell ,

* E-mail: jeff.rathmell@duke.edu (JCR); a.n.macintyre@duke.edu (ANM)

Affiliation Department of Pharmacology and Cancer Biology, Department of Immunology, Sarah W. Stedman Center for Nutrition and Metabolism, Duke University, Durham, NC, United States of America
⨯
Andrew N. Macintyre

* E-mail: jeff.rathmell@duke.edu (JCR); a.n.macintyre@duke.edu (ANM)

Affiliation Department of Pharmacology and Cancer Biology, Department of Immunology, Sarah W. Stedman Center for Nutrition and Metabolism, Duke University, Durham, NC, United States of America
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Cytotoxic T cells
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T cells
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Cell metabolism
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T helper cells
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Mitochondria
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Glycolysis
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Glucose metabolism
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CD coreceptors
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