Bordetella Adenylate Cyclase Toxin Differentially Modulates Toll-Like Receptor-Stimulated Activation, Migration and T Cell Stimulatory Capacity of Dendritic Cells

Irena Adkins; Jana Kamanova; Aneta Kocourkova; Martina Svedova; Jakub Tomala; Hana Janova; Jiri Masin; Barbora Chladkova; Ladislav Bumba; Marek Kovar; Padraig J. Ross; Ludmila Tuckova; Radek Spisek; Kingston H. G. Mills; Peter Sebo

doi:10.1371/journal.pone.0104064

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Peer-reviewed

Research Article

Bordetella Adenylate Cyclase Toxin Differentially Modulates Toll-Like Receptor-Stimulated Activation, Migration and T Cell Stimulatory Capacity of Dendritic Cells

Irena Adkins ,

* E-mail: adkins@sotio.com

Affiliation Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Jana Kamanova,

Affiliation Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Aneta Kocourkova,

Affiliation Institute of Immunology, Charles University, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic
⨯
Martina Svedova,

Affiliation Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Jakub Tomala,

Affiliation Laboratory of Tumor Immunology, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Hana Janova,

Affiliation Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Jiri Masin,

Affiliation Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Barbora Chladkova,

Affiliation Laboratory of Specific Cellular Immunity, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Ladislav Bumba,

Affiliation Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Marek Kovar,

Affiliation Laboratory of Tumor Immunology, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Padraig J. Ross,

Affiliation Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
⨯
Ludmila Tuckova,

Affiliation Laboratory of Specific Cellular Immunity, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Radek Spisek,

Affiliation Institute of Immunology, Charles University, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic
⨯
Kingston H. G. Mills,

Affiliation Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
⨯
Peter Sebo

Affiliation Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯

Bordetella Adenylate Cyclase Toxin Differentially Modulates Toll-Like Receptor-Stimulated Activation, Migration and T Cell Stimulatory Capacity of Dendritic Cells

Irena Adkins,
Jana Kamanova,
Aneta Kocourkova,
Martina Svedova,
Jakub Tomala,
Hana Janova,
Jiri Masin,
Barbora Chladkova,
Ladislav Bumba,
Marek Kovar

Published: August 1, 2014
https://doi.org/10.1371/journal.pone.0104064

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