Functional Balance between the Hemagglutinin and Neuraminidase of Influenza A(H1N1)pdm09 HA D222 Variants

Jean-Sébastien Casalegno; Olivier Ferraris; Vanessa Escuret; Maude Bouscambert; Corinne Bergeron; Laetitia Linès; Thierry Excoffier; Martine Valette; Emilie Frobert; Sylvie Pillet; Bruno Pozzetto; Bruno Lina; Michèle Ottmann

doi:10.1371/journal.pone.0104009

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Research Article

Functional Balance between the Hemagglutinin and Neuraminidase of Influenza A(H1N1)pdm09 HA D222 Variants

Jean-Sébastien Casalegno ,

* E-mail: jean-sebastien.casalegno@chu-lyon.fr

¶J-SC and EF are first co-authors on this work.

Affiliations Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Laboratoire de Virologie et Pathologie Humaine, EA 4610, Lyon, France, Laboratory of Virology, National Influenza Centre (South of France), Hospices Civils de Lyon, Bât A3, Bron, France
⨯
Olivier Ferraris ,

¶J-SC and EF are first co-authors on this work.

Affiliations Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Laboratoire de Virologie et Pathologie Humaine, EA 4610, Lyon, France, IRBA, Equipe Recherche Lyon, Lyon, France
⨯
Vanessa Escuret,

Affiliations Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Laboratoire de Virologie et Pathologie Humaine, EA 4610, Lyon, France, Laboratory of Virology, National Influenza Centre (South of France), Hospices Civils de Lyon, Bât A3, Bron, France
⨯
Maude Bouscambert,

Affiliations Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Laboratoire de Virologie et Pathologie Humaine, EA 4610, Lyon, France, Laboratory of Virology, National Influenza Centre (South of France), Hospices Civils de Lyon, Bât A3, Bron, France
⨯
Corinne Bergeron,

Affiliation Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Laboratoire de Virologie et Pathologie Humaine, EA 4610, Lyon, France
⨯
Laetitia Linès,

Affiliation Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Laboratoire de Virologie et Pathologie Humaine, EA 4610, Lyon, France
⨯
Thierry Excoffier,

Affiliation Université de Lyon, Université Lyon 1, Université Lyon 2, INSA de Lyon, École Centrale de Lyon, LIRIS UMR 5205 CNRS, Lyon, France
⨯
Martine Valette,

Affiliation Laboratory of Virology, National Influenza Centre (South of France), Hospices Civils de Lyon, Bât A3, Bron, France
⨯
Emilie Frobert,

Affiliations Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Laboratoire de Virologie et Pathologie Humaine, EA 4610, Lyon, France, Laboratory of Virology, National Influenza Centre (South of France), Hospices Civils de Lyon, Bât A3, Bron, France
⨯
Sylvie Pillet,

Affiliation Laboratoire de Bactériologie-virologie-hygiène, Hôpital Nord, CHU de Saint-Étienne, Saint-Étienne, France
⨯
Bruno Pozzetto,

Affiliation Laboratoire de Bactériologie-virologie-hygiène, Hôpital Nord, CHU de Saint-Étienne, Saint-Étienne, France
⨯
Bruno Lina,

Affiliations Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Laboratoire de Virologie et Pathologie Humaine, EA 4610, Lyon, France, Laboratory of Virology, National Influenza Centre (South of France), Hospices Civils de Lyon, Bât A3, Bron, France
⨯
Michèle Ottmann

Affiliation Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Laboratoire de Virologie et Pathologie Humaine, EA 4610, Lyon, France
⨯

Functional Balance between the Hemagglutinin and Neuraminidase of Influenza A(H1N1)pdm09 HA D222 Variants

Jean-Sébastien Casalegno,
Olivier Ferraris,
Vanessa Escuret,
Maude Bouscambert,
Corinne Bergeron,
Laetitia Linès,
Thierry Excoffier,
Martine Valette,
Emilie Frobert,
Sylvie Pillet

Published: August 13, 2014
https://doi.org/10.1371/journal.pone.0104009

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