Decreased DGCR8 Expression and miRNA Dysregulation in Individuals with 22q11.2 Deletion Syndrome

Chantal Sellier; Vicki J. Hwang; Ravi Dandekar; Blythe Durbin-Johnson; Nicolas Charlet-Berguerand; Bradley P. Ander; Frank R. Sharp; Kathleen Angkustsiri; Tony J. Simon; Flora Tassone

doi:10.1371/journal.pone.0103884

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Open Access

Peer-reviewed

Research Article

Decreased DGCR8 Expression and miRNA Dysregulation in Individuals with 22q11.2 Deletion Syndrome

Chantal Sellier,

Affiliation Institute of Genetics and Molecular and Cellular Biology, University of Strasbourg, Strasbourg, France
⨯
Vicki J. Hwang,

Affiliation Department of Biochemistry and Molecular Medicine, University of California Davis, Sacramento, California, United States of America
⨯
Ravi Dandekar,

Affiliation Department of Biochemistry and Molecular Medicine, University of California Davis, Sacramento, California, United States of America
⨯
Blythe Durbin-Johnson,

Affiliation Department of Public Health Sciences, UC Davis Medical Center, Sacramento, California, United States of America
⨯
Nicolas Charlet-Berguerand,

Affiliation Institute of Genetics and Molecular and Cellular Biology, University of Strasbourg, Strasbourg, France
⨯
Bradley P. Ander,

Affiliations MIND Institute, UC Davis Medical Center, Sacramento, California, United States of America, Department of Neurology, UC Davis Medical Center, Sacramento, California, United States of America
⨯
Frank R. Sharp,

Affiliations MIND Institute, UC Davis Medical Center, Sacramento, California, United States of America, Department of Neurology, UC Davis Medical Center, Sacramento, California, United States of America
⨯
Kathleen Angkustsiri,

Affiliations MIND Institute, UC Davis Medical Center, Sacramento, California, United States of America, Department of Pediatrics, UC Davis Medical Center, Sacramento, California, United States of America
⨯
Tony J. Simon,

Affiliations MIND Institute, UC Davis Medical Center, Sacramento, California, United States of America, Department of Psychiatry, UC Davis Medical Center, Sacramento, California, United States of America
⨯
Flora Tassone

* E-mail: ftassone@ucdavis.edu

Affiliations Department of Biochemistry and Molecular Medicine, University of California Davis, Sacramento, California, United States of America, MIND Institute, UC Davis Medical Center, Sacramento, California, United States of America
⨯

Decreased DGCR8 Expression and miRNA Dysregulation in Individuals with 22q11.2 Deletion Syndrome

Chantal Sellier,
Vicki J. Hwang,
Ravi Dandekar,
Blythe Durbin-Johnson,
Nicolas Charlet-Berguerand,
Bradley P. Ander,
Frank R. Sharp,
Kathleen Angkustsiri,
Tony J. Simon,
Flora Tassone

Published: August 1, 2014
https://doi.org/10.1371/journal.pone.0103884

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