Choice of Non-Inferiority (NI) Margins Does Not Protect against Degradation of Treatment Effects on an Average – An Observational Study of Registered and Published NI Trials

Open Access

Peer-reviewed

Research Article

Beryl Primrose Gladstone ,

* E-mail: beryl@imbi.uni-freiburg.de

Affiliation Clinical Epidemiology Group, Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg, Germany
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Werner Vach

Affiliation Clinical Epidemiology Group, Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg, Germany
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