Identification of Polyketide Inhibitors Targeting 3-Dehydroquinate Dehydratase in the Shikimate Pathway of Enterococcus faecalis

• Vivian Wing Ngar Cheung ,

  Contributed equally to this work with: Vivian Wing Ngar Cheung, Bo Xue

  Affiliation Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Bo Xue ,

  Contributed equally to this work with: Vivian Wing Ngar Cheung, Bo Xue

  Affiliation Institute of Molecular and Cell Biology, Singapore, Singapore

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• Maria Hernandez-Valladares,

  Affiliation Institute of Molecular and Cell Biology, Singapore, Singapore

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• Maybelle Kho Go,

  Affiliation Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Alvin Tung,

  Affiliation Institute of Molecular and Cell Biology, Singapore, Singapore

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• Adeleke H. Aguda,

  Affiliation Institute of Molecular and Cell Biology, Singapore, Singapore

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• Robert C. Robinson ,

  * E-mail: rrobinson@imcb.a-star.edu.sg (RCR); bchyws@nus.edu.sg (WSY)

  Affiliations Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Institute of Molecular and Cell Biology, Singapore, Singapore

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• Wen Shan Yew

  * E-mail: rrobinson@imcb.a-star.edu.sg (RCR); bchyws@nus.edu.sg (WSY)

  Affiliations Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Synthetic Biology Research Consortium, National University of Singapore, Singapore, Singapore

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