Crystal Structure of the Stress-Inducible Human Heat Shock Protein 70 Substrate-Binding Domain in Complex with Peptide Substrate

Open Access

Peer-reviewed

Research Article

Pingfeng Zhang,

Affiliations Program in Gene Expression and Regulation, The Wistar Institute, Philadelphia, Pennsylvania, United States of America, Department of Biochemistry & Biophysics, Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Julia I-Ju Leu ,

* E-mail: leu@mail.med.upenn.edu (JI-JL) (JL); marmor@mail.med.upenn.edu (RM) (RM)

Affiliation Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Maureen E. Murphy,

Affiliation Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania, United States of America
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Donna L. George,

Affiliation Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Ronen Marmorstein

* E-mail: leu@mail.med.upenn.edu (JI-JL) (JL); marmor@mail.med.upenn.edu (RM) (RM)

Affiliations Program in Gene Expression and Regulation, The Wistar Institute, Philadelphia, Pennsylvania, United States of America, Department of Biochemistry & Biophysics, Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Crystal structure
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DNA structure
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Protein structure
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Protein structure comparison
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Eukaryota
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Heat shock response
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Protein structure determination
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Hydrogen bonding
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