Mung Bean Nuclease Treatment Increases Capture Specificity of Microdroplet-PCR Based Targeted DNA Enrichment

Open Access

Peer-reviewed

Research Article

Zhenming Yu ,

* E-mail: yuz2@email.chop.edu (ZY) (ZY); santani@email.chop.edu (ABS) (AS)

Affiliation Division of Genomic Diagnostics and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Kajia Cao,

Affiliation Division of Genomic Diagnostics and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Tanya Tischler,

Affiliation Division of Genomic Diagnostics and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Catherine A. Stolle,

Affiliation Division of Genomic Diagnostics and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Avni B. Santani

* E-mail: yuz2@email.chop.edu (ZY) (ZY); santani@email.chop.edu (ABS) (AS)

Affiliations Division of Genomic Diagnostics and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Nucleases
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Genomics
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Polymerase chain reaction
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DNA repair
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DNA libraries
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Genomic libraries
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Genome sequencing
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Human genomics
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