Roles of PI3K/Akt and c-Jun Signaling Pathways in Human Papillomavirus Type 16 Oncoprotein-Induced HIF-1α, VEGF, and IL-8 Expression and In Vitro Angiogenesis in Non-Small Cell Lung Cancer Cells

Open Access

Peer-reviewed

Research Article

Erying Zhang ,

Contributed equally to this work with: Erying Zhang, Xiaowei Feng

Affiliations Institute of Biochemistry and Molecular Biology, Guangdong Medical College, Zhanjiang, Guangdong, China, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical College, Zhanjiang, Guangdong, China
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Xiaowei Feng ,

Contributed equally to this work with: Erying Zhang, Xiaowei Feng

Affiliations Institute of Biochemistry and Molecular Biology, Guangdong Medical College, Zhanjiang, Guangdong, China, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical College, Zhanjiang, Guangdong, China
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Fei Liu,

Affiliations Institute of Biochemistry and Molecular Biology, Guangdong Medical College, Zhanjiang, Guangdong, China, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical College, Zhanjiang, Guangdong, China
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Peihua Zhang,

Affiliation Institute of Plastic Surgery, Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, China
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Jie Liang,

Affiliation Institute of Plastic Surgery, Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, China
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Xudong Tang

* E-mail: tangxudong2599@126.com

Affiliations Institute of Biochemistry and Molecular Biology, Guangdong Medical College, Zhanjiang, Guangdong, China, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical College, Zhanjiang, Guangdong, China
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HPV-16
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Non-small cell lung cancer
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Angiogenesis
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VEGF signaling
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Small interfering RNA
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Protein expression
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Transfection
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MAPK signaling cascades
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