Combined Influence of EGF+61G>A and TGFB+869T>C Functional Polymorphisms in Renal Cell Carcinoma Progression and Overall Survival: The Link to Plasma Circulating MiR-7 and MiR-221/222 Expression

Ana L. Teixeira; Francisca Dias; Marta Ferreira; Mónica Gomes; Juliana I. Santos; Francisco Lobo; Joaquina Maurício; José Carlos Machado; Rui Medeiros

doi:10.1371/journal.pone.0103258

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Research Article

Combined Influence of EGF+61G>A and TGFB+869T>C Functional Polymorphisms in Renal Cell Carcinoma Progression and Overall Survival: The Link to Plasma Circulating MiR-7 and MiR-221/222 Expression

Ana L. Teixeira,

Affiliations Molecular Oncology Group & Virology Pathology, Portuguese Institute of Oncology of Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences (ICBAS) of University of Porto, Porto, Portugal, Research Department, Portuguese League Against Cancer (NRNorte), Porto, Portugal
⨯
Francisca Dias,

Affiliations Molecular Oncology Group & Virology Pathology, Portuguese Institute of Oncology of Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences (ICBAS) of University of Porto, Porto, Portugal, Research Department, Portuguese League Against Cancer (NRNorte), Porto, Portugal
⨯
Marta Ferreira,

Affiliation Oncology Department, Portuguese Institute of Oncology of Porto, Porto, Portugal
⨯
Mónica Gomes,

Affiliations Molecular Oncology Group & Virology Pathology, Portuguese Institute of Oncology of Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences (ICBAS) of University of Porto, Porto, Portugal, Research Department, Portuguese League Against Cancer (NRNorte), Porto, Portugal
⨯
Juliana I. Santos,

Affiliations Molecular Oncology Group & Virology Pathology, Portuguese Institute of Oncology of Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences (ICBAS) of University of Porto, Porto, Portugal
⨯
Francisco Lobo,

Affiliation Urology Department, Portuguese Institute of Oncology of Porto, Porto, Portugal
⨯
Joaquina Maurício,

Affiliation Oncology Department, Portuguese Institute of Oncology of Porto, Porto, Portugal
⨯
José Carlos Machado,

Affiliations Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal, Faculty of Medicine- University of Porto, Porto, Portugal
⨯
Rui Medeiros

* E-mail: ruimedei@ipoporto.min-saude.pt

Affiliations Molecular Oncology Group & Virology Pathology, Portuguese Institute of Oncology of Porto, Porto, Portugal, Abel Salazar Institute for the Biomedical Sciences (ICBAS) of University of Porto, Porto, Portugal, Research Department, Portuguese League Against Cancer (NRNorte), Porto, Portugal, Faculty of Health Sciences of Fernando Pessoa University, Porto, Portugal
⨯

Combined Influence of EGF+61G>A and TGFB+869T>C Functional Polymorphisms in Renal Cell Carcinoma Progression and Overall Survival: The Link to Plasma Circulating MiR-7 and MiR-221/222 Expression

Ana L. Teixeira,
Francisca Dias,
Marta Ferreira,
Mónica Gomes,
Juliana I. Santos,
Francisco Lobo,
Joaquina Maurício,
José Carlos Machado,
Rui Medeiros

Published: April 24, 2015
https://doi.org/10.1371/journal.pone.0103258

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