BMP-Non-Responsive Sca1+CD73+CD44+ Mouse Bone Marrow Derived Osteoprogenitor Cells Respond to Combination of VEGF and BMP-6 to Display Enhanced Osteoblastic Differentiation and Ectopic Bone Formation

Open Access

Peer-reviewed

Research Article

BMP-Non-Responsive Sca1⁺CD73⁺CD44⁺ Mouse Bone Marrow Derived Osteoprogenitor Cells Respond to Combination of VEGF and BMP-6 to Display Enhanced Osteoblastic Differentiation and Ectopic Bone Formation

Vedavathi Madhu,

Affiliation Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, United States of America
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Ching-Ju Li,

Affiliation Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, United States of America
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Abhijit S. Dighe,

Affiliation Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, United States of America
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Gary Balian,

Affiliation Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, United States of America
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Quanjun Cui

* E-mail: QC4Q@hscmail.mcc.virginia.edu

Affiliation Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, United States of America
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Mesenchymal stem cells
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Bone development
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Bone fracture
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Gene expression
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Ossification
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Medical implants
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Alizarin staining
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Polymerase chain reaction
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