Tyrosine Phosphatase Shp2 Mediates the Estrogen Biological Action in Breast Cancer via Interaction with the Estrogen Extranuclear Receptor

Jun Li; Yujia Kang; Longgang Wei; Wenjie Liu; Yingpu Tian; Baozhen Chen; Xiandong Lin; Yang Li; Gen-Sheng Feng; Zhongxian Lu

doi:10.1371/journal.pone.0102847

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Open Access

Peer-reviewed

Research Article

Tyrosine Phosphatase Shp2 Mediates the Estrogen Biological Action in Breast Cancer via Interaction with the Estrogen Extranuclear Receptor

Jun Li ,

Contributed equally to this work with: Jun Li, Yujia Kang

Affiliation Xiamen City Key Lab of Metabolism Disease & School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Yujia Kang ,

Contributed equally to this work with: Jun Li, Yujia Kang

Affiliation Xiamen City Key Lab of Metabolism Disease & School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Longgang Wei,

Affiliation Xiamen City Key Lab of Metabolism Disease & School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Wenjie Liu,

Affiliation Xiamen City Key Lab of Metabolism Disease & School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Yingpu Tian,

Affiliation Xiamen City Key Lab of Metabolism Disease & School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Baozhen Chen,

Affiliation Department of Pathology, Fujian Provincial Tumor Hospital, Fuzhou, Fujian, China
⨯
Xiandong Lin,

Affiliation Department of Pathology, Fujian Provincial Tumor Hospital, Fuzhou, Fujian, China
⨯
Yang Li,

Affiliation Xiamen City Key Lab of Metabolism Disease & School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Gen-Sheng Feng,

Affiliation Department of Pathology & Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America
⨯
Zhongxian Lu

* E-mail: zhongxian@xmu.edu.cn

Affiliation Xiamen City Key Lab of Metabolism Disease & School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯

Tyrosine Phosphatase Shp2 Mediates the Estrogen Biological Action in Breast Cancer via Interaction with the Estrogen Extranuclear Receptor

Jun Li,
Yujia Kang,
Longgang Wei,
Wenjie Liu,
Yingpu Tian,
Baozhen Chen,
Xiandong Lin,
Yang Li,
Gen-Sheng Feng,
Zhongxian Lu

Published: July 21, 2014
https://doi.org/10.1371/journal.pone.0102847

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