Diabetic Osteopenia by Decreased β-Catenin Signaling Is Partly Induced by Epigenetic Derepression of sFRP-4 Gene

Kiyoshi Mori; Riko Kitazawa; Takeshi Kondo; Michiko Mori; Yasuhiro Hamada; Michiru Nishida; Yasuhiro Minami; Ryuma Haraguchi; Yutaka Takahashi; Sohei Kitazawa

doi:10.1371/journal.pone.0102797

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Peer-reviewed

Research Article

Diabetic Osteopenia by Decreased β-Catenin Signaling Is Partly Induced by Epigenetic Derepression of sFRP-4 Gene

Kiyoshi Mori,

Affiliations Department of Pathology, Division of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, Kobe City, Japan, Department of Pathology, National Hospital Organization, Osaka National Hospital, Hoenzaka, Chuo-ku, Osaka City, Japan
⨯
Riko Kitazawa,

Affiliations Department of Pathology, Division of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, Kobe City, Japan, Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, Japan, Department of Diagnostic Pathology, Ehime University Hospital, Shitsukawa, Toon City, Ehime, Japan
⨯
Takeshi Kondo,

Affiliations Department of Pathology, Division of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, Kobe City, Japan, Department of Legal Medicine, Kobe University Graduate School of Medicine, Kobe City, Japan
⨯
Michiko Mori,

Affiliation Department of Pathology, Division of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, Kobe City, Japan
⨯
Yasuhiro Hamada,

Affiliation Department of Therapeutic Nutrition, Institute of Health Bioscience, The University of Tokushima, Tokushima City, Japan
⨯
Michiru Nishida,

Affiliation Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe City, Japan
⨯
Yasuhiro Minami,

Affiliation Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe City, Japan
⨯
Ryuma Haraguchi,

Affiliation Department of Diagnostic Pathology, Ehime University Hospital, Shitsukawa, Toon City, Ehime, Japan
⨯
Yutaka Takahashi,

Affiliation Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe City, Japan
⨯
Sohei Kitazawa

* E-mail: kitazawa@m.ehime-u.ac.jp

Affiliations Department of Pathology, Division of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, Kobe City, Japan, Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, Japan, Department of Diagnostic Pathology, Ehime University Hospital, Shitsukawa, Toon City, Ehime, Japan
⨯

Diabetic Osteopenia by Decreased β-Catenin Signaling Is Partly Induced by Epigenetic Derepression of sFRP-4 Gene

Kiyoshi Mori,
Riko Kitazawa,
Takeshi Kondo,
Michiko Mori,
Yasuhiro Hamada,
Michiru Nishida,
Yasuhiro Minami,
Ryuma Haraguchi,
Yutaka Takahashi,
Sohei Kitazawa

Published: July 18, 2014
https://doi.org/10.1371/journal.pone.0102797

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