Germinal Center B Cell Depletion Diminishes CD4+ Follicular T Helper Cells in Autoimmune Mice

Isharat Yusuf; Jessica Stern; Tom M. McCaughtry; Sandra Gallagher; Hong Sun; Changshou Gao; Thomas Tedder; Gianluca Carlesso; Laura Carter; Ronald Herbst; Yue Wang

doi:10.1371/journal.pone.0102791

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Peer-reviewed

Research Article

Germinal Center B Cell Depletion Diminishes CD4⁺ Follicular T Helper Cells in Autoimmune Mice

Isharat Yusuf,

Affiliation Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯
Jessica Stern,

Affiliation Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯
Tom M. McCaughtry,

Affiliation Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯
Sandra Gallagher,

Affiliation Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯
Hong Sun,

Affiliation Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯
Changshou Gao,

Affiliation Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯
Thomas Tedder,

Affiliation Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Gianluca Carlesso,

Affiliation Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯
Laura Carter,

Affiliation Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯
Ronald Herbst,

Affiliation Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯
Yue Wang

* E-mail: wangy@medimmune.com

Affiliation Department of Respiratory, Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, Maryland, United States of America
⨯

Germinal Center B Cell Depletion Diminishes CD4⁺ Follicular T Helper Cells in Autoimmune Mice

Isharat Yusuf,
Jessica Stern,
Tom M. McCaughtry,
Sandra Gallagher,
Hong Sun,
Changshou Gao,
Thomas Tedder,
Gianluca Carlesso,
Laura Carter,
Ronald Herbst

Published: August 7, 2014
https://doi.org/10.1371/journal.pone.0102791

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