The Cellular Prion Protein Negatively Regulates Phagocytosis and Cytokine Expression in Murine Bone Marrow-Derived Macrophages

Min Wang; Deming Zhao; Yang Yang; Jin Liu; Jin Wang; Xiaomin Yin; Lifeng Yang; Xiangmei Zhou

doi:10.1371/journal.pone.0102785

Loading metrics

Open Access

Peer-reviewed

Research Article

The Cellular Prion Protein Negatively Regulates Phagocytosis and Cytokine Expression in Murine Bone Marrow-Derived Macrophages

Min Wang ,

Contributed equally to this work with: Min Wang, Deming Zhao

Affiliation State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China
⨯
Deming Zhao ,

Contributed equally to this work with: Min Wang, Deming Zhao

Affiliation State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China
⨯
Yang Yang,

Affiliation State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China
⨯
Jin Liu,

Affiliation State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China
⨯
Jin Wang,

Affiliation State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China
⨯
Xiaomin Yin,

Affiliation State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China
⨯
Lifeng Yang,

Affiliation State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China
⨯
Xiangmei Zhou

* E-mail: zhouxm@cau.edu.cn

Affiliation State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China
⨯

The Cellular Prion Protein Negatively Regulates Phagocytosis and Cytokine Expression in Murine Bone Marrow-Derived Macrophages

Min Wang,
Deming Zhao,
Yang Yang,
Jin Liu,
Jin Wang,
Xiaomin Yin,
Lifeng Yang,
Xiangmei Zhou

Published: July 24, 2014
https://doi.org/10.1371/journal.pone.0102785

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Phagocytosis
Is the Subject Area "Phagocytosis" applicable to this article?

Thanks for your feedback.
Phagosomes
Is the Subject Area "Phagosomes" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Escherichia coli infections
Is the Subject Area "Escherichia coli infections" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Messenger RNA
Is the Subject Area "Messenger RNA" applicable to this article?

Thanks for your feedback.
Prion diseases
Is the Subject Area "Prion diseases" applicable to this article?

Thanks for your feedback.