Functional and Molecular Characterization of Hyposensitive Underactive Bladder Tissue and Urine in Streptozotocin-Induced Diabetic Rat

Jayabalan Nirmal; Pradeep Tyagi; Yao-Chi Chuang; Wei-Chia Lee; Naoki Yoshimura; Chao-Cheng Huang; Bharathi Rajaganapathy; Michael B. Chancellor

doi:10.1371/journal.pone.0102644

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Peer-reviewed

Research Article

Functional and Molecular Characterization of Hyposensitive Underactive Bladder Tissue and Urine in Streptozotocin-Induced Diabetic Rat

Jayabalan Nirmal ,

Contributed equally to this work with: Jayabalan Nirmal, Pradeep Tyagi

Affiliation Department of Urology, Centre for Urology Research Excellence, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States of America
⨯
Pradeep Tyagi ,

Contributed equally to this work with: Jayabalan Nirmal, Pradeep Tyagi

Affiliation Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Yao-Chi Chuang ,

* E-mail: chuang82@ms26.hinet.net

Affiliation Department of Urology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Wei-Chia Lee,

Affiliation Department of Urology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Naoki Yoshimura,

Affiliation Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Chao-Cheng Huang,

Affiliation Department of Pathology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Bharathi Rajaganapathy,

Affiliation Department of Urology, Centre for Urology Research Excellence, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States of America
⨯
Michael B. Chancellor

Affiliation Department of Urology, Centre for Urology Research Excellence, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States of America
⨯

Functional and Molecular Characterization of Hyposensitive Underactive Bladder Tissue and Urine in Streptozotocin-Induced Diabetic Rat

Jayabalan Nirmal,
Pradeep Tyagi,
Yao-Chi Chuang,
Wei-Chia Lee,
Naoki Yoshimura,
Chao-Cheng Huang,
Bharathi Rajaganapathy,
Michael B. Chancellor

Published: July 22, 2014
https://doi.org/10.1371/journal.pone.0102644

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Diabetes mellitus
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Urine
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Muscle contraction
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